Protein: ACS1
Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA ligase 1) (Acyl-activating enzyme 1)

Gene: ACS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 27
UniProt ID: Q01574

Gene Ontology (top 5):
GO:0003987 - acetate-CoA ligase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1031087

ACS1
Acetyl-coenzyme A synthetase 1

1

9

Small-scale

0.647

High

763973

SPT10
Protein SPT10

1

0

High-throughput

0.586

High

579913

HSC82
ATP-dependent molecular chaperone HSC82

2

5

High-throughput

0.584

High

1009811

CACM
Putative mitochondrial carnitine O-acetyltransferase

1

2

High-throughput

0.541

High

1031088

IMA1
Importin subunit alpha

1

1

High-throughput

0.541

High

452755

ADR1
Regulatory protein ADR1

1

1

High-throughput

0.508

High

365156

KPYK1
Pyruvate kinase 1

1

1

Small-scale

0.479

High

393191

HSP82
ATP-dependent molecular chaperone HSP82

1

5

High-throughput

0.479

High

649657

KCC2
Calcium/calmodulin-dependent protein kinase II

1

1

High-throughput

0.479

High

679981

CDC48
Cell division control protein 48

1

2

High-throughput

0.479

High

735117

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

748003

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

808887

UME6
Transcriptional regulatory protein UME6

1

1

High-throughput

0.479

High

1031089

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

1031091

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.479

High

1031094

SMC6
Structural maintenance of chromosomes protein 6

1

1

High-throughput

0.479

High

764143

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

864807

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.458

High

918658

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

919076

YG2W
Uncharacterized protein YGR111W

1

0

High-throughput

0.458

High

925368

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

1031090

PEX30
Peroxisomal membrane protein PEX30

1

0

Small-scale

0.458

High

1031095

YN034
Uncharacterized protein YNR034W-A

1

0

Small-scale

0.458

High

1031096

RGS2
Regulator of G-protein signaling 2

1

0

High-throughput

0.458

High

1031092

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

1031093

YL049
Uncharacterized protein YLR049C

1

0

High-throughput

0.282

High


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Last updated: 11Aug2025