HitPredict

Interactor 1: NEK8 (Q86SG6)
Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (Nima-related protein kinase 12a)
Gene: NEK8

Interactor 2: DNJC7 (Q99615)
DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2)
Gene: DNAJC7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	DnaJ~Pkinase
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 692 Hs			1 494
+	Hs
		684848 NEK8_HUMAN (1-692): 0: 727: 100.00		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		1197683 NEK8_HUMAN (1-692): 0: 727: 100.00		RPAP3_HUMAN (2-223): 2.82e-09: 61.6: 11.92
+	Hs
		684908 NEK9_HUMAN (3-689): 0: 603: 34.37		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		174861 KCC2G_HUMAN (2-401): 7.59e-121: 373: 23.80		OGT1_HUMAN (3-401): 1.62e-31: 130: 13.59
+	Mm
		1141233 KCC2G_MOUSE (2-401): 1.7e-126: 387: 22.06		PPP5_MOUSE (139-260): 3.58e-16: 82.8: 13.93
+	Hs
		319984 HERC2_HUMAN (314-460): 2.25e-09: 63.2: 31.68		DNJC7_HUMAN (1-494): 2.58e-85: 273: 100.00
+	Hs
		851624 NEK4_HUMAN (1-313): 5.52e-60: 218: 37.14		TTC28_HUMAN (1-320): 1.04e-19: 95.1: 15.27
+	Hs
		672791 NEK3_HUMAN (1-260): 3.03e-53: 193: 36.78		CDC27_HUMAN (4-128): 1.63e-15: 81.6: 20.80
+	Hs
		672790 NEK2_HUMAN (2-257): 1.17e-53: 192: 40.23		CDC27_HUMAN (4-128): 1.63e-15: 81.6: 20.80
+	Hs
		684829 NEK10_HUMAN (10-290): 3.19e-36: 148: 31.68		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		279267 HERC2_HUMAN (314-460): 2.25e-09: 63.2: 31.68		DNJB5_HUMAN (380-491): 5.82e-19: 90.1: 43.31
+	Hs
		319931 HERC2_HUMAN (314-460): 2.25e-09: 63.2: 31.68		DNJB8_HUMAN (381-482): 1.21e-15: 78.2: 44.35