HitPredict

Interactor 1: PATL1 (Q86TB9)
Protein PAT1 homolog 1 (PAT1-like protein 1) (Protein PAT1 homolog b) (Pat1b) (hPat1b)
Gene: PATL1

Interactor 2: XRN1 (Q8IZH2)
5'-3' exoribonuclease 1 (EC 3.1.13.-) (Strand-exchange protein 1 homolog)
Gene: XRN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.588

Property	Details
Experiments	29395067, 20584987
Identification Methods	proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0003723 - RNA binding GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 770 Hs			1 1706
+	Hs
		87374 PATL2_HUMAN (264-765): 1.91e-97: 314: 32.54		XRN1_HUMAN (1-1706): 0: 2785: 100.00
+	Sc
		604930 PAT1_YEAST (178-765): 1.32e-74: 259: 16.38		XRN1_YEAST (1-1267): 0: 1403: 32.34
+	Hs
		1319409 WDR33_HUMAN (13-405): 7.81e-09: 61.5: 15.04		XRN2_HUMAN (1-700): 0: 978: 34.46
+	Sc
		635915 PAT1_YEAST (178-765): 1.32e-74: 259: 16.38		XRN2_YEAST (349-719): 4.07e-110: 377: 24.55
+	Sp
		194956 PAT1_SCHPO (154-761): 6.3e-69: 243: 17.65		XRN2_SCHPO (366-609): 3.59e-93: 328: 36.07