HitPredict

Interactor 1: PB1 (Q86U86)
Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D)
Gene: PBRM1

Interactor 2: SMRCD (Q9H4L7)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.4.12) (ATP-dependent helicase 1) (hHEL1)
Gene: SMARCAD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21549307
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1689 Hs			1 1026
+	Hs
		847007 PB1_HUMAN (1-1689): 0: 1223: 100.00		SMCA4_HUMAN (96-1024): 0: 693: 26.54
+	Hs
		846812 PB1_HUMAN (1-1689): 0: 1223: 100.00		SMCA2_HUMAN (55-1024): 0: 689: 25.05
+	Hs
		1199209 PB1_HUMAN (1-1689): 0: 1223: 100.00		CHD7_HUMAN (23-1021): 0: 683: 22.57
+	Mm
		101533 F8VQD1_MOUSE (1-1689): 0: 1207: 97.30		SMCA4_MOUSE (96-1024): 0: 692: 26.43
+	Mm
		101535 F8VQD1_MOUSE (1-1689): 0: 1207: 97.30		SMCA2_MOUSE (60-1024): 0: 692: 24.98
+	Hs
		1199201 PB1_HUMAN (1-1689): 0: 1223: 100.00		CHD8_HUMAN (181-1021): 0: 641: 23.28
+	Mm
		1111945 PB1_MOUSE (1-1689): 0: 1168: 91.95		SMCA4_MOUSE (96-1024): 0: 692: 26.43
+	Hs
		1018557 PB1_HUMAN (1-1689): 0: 1223: 100.00		CHD3_HUMAN (338-1022): 0: 621: 27.64
+	Dm
		631317 Q9VC36_DROME (1-1458): 0: 711: 34.35		BRM_DROME (55-1024): 0: 656: 25.69
+	Hs
		847093 BRWD1_HUMAN (2-959): 3.8e-58: 224: 12.26		SMCA4_HUMAN (96-1024): 0: 693: 26.54
+	Hs
		600103 TAF1_HUMAN (457-963): 1.08e-57: 223: 16.79		SMCA2_HUMAN (55-1024): 0: 689: 25.05
+	Hs
		847033 PHIP_HUMAN (480-1024): 4.44e-53: 207: 13.50		SMCA4_HUMAN (96-1024): 0: 693: 26.54
+	Hs
		229313 DNMT1_HUMAN (301-1361): 1.76e-75: 280: 12.20		SMCA5_HUMAN (353-1021): 0: 594: 29.60
+	Hs
		600135 TAF1_HUMAN (457-963): 1.08e-57: 223: 16.79		CHD3_HUMAN (338-1022): 0: 621: 27.64
+	Hs
		1255033 PHIP_HUMAN (480-1024): 4.44e-53: 207: 13.50		CHD5_HUMAN (338-1022): 0: 629: 27.78
+	Hs
		229448 PHIP_HUMAN (480-1024): 4.44e-53: 207: 13.50		SMCA5_HUMAN (353-1021): 0: 594: 29.60
+	Hs
		641288 DNMT1_HUMAN (301-1361): 1.76e-75: 280: 12.20		HELLS_HUMAN (479-999): 1.2e-93: 318: 37.59
+	Sc
		744895 RSC4_YEAST (1-426): 1.18e-50: 192: 17.50		ISW1_YEAST (486-999): 7.99e-79: 282: 37.26
+	Sc
		696241 RSC4_YEAST (1-426): 1.18e-50: 192: 17.50		STH1_YEAST (486-1021): 6.37e-78: 281: 35.31
+	Sc
		697424 RSC4_YEAST (1-426): 1.18e-50: 192: 17.50		CHD1_YEAST (497-998): 1.71e-77: 280: 37.55