Protein: MED9
Mediator of RNA polymerase II transcription subunit 9 (Mediator complex subunit 9)

Gene: MED9
Organism: Homo sapiens
Interactions: 121
UniProt ID: Q9NWA0

Gene Ontology (top 5):
GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016592 - mediator complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1342922

MED4
Mediator of RNA polymerase II transcription subunit 4

8

1

Small-scale

0.975

High

1076205

MED1
Mediator of RNA polymerase II transcription subunit 1

9

0

Small-scale

0.923

High

1037105

MED21
Mediator of RNA polymerase II transcription subunit 21

8

0

Small-scale

0.921

High

826365

CDK8
Cyclin-dependent kinase 8

13

2

Small-scale

0.761

High

1314885

CDK19
Cyclin-dependent kinase 19

8

2

High-throughput

0.752

High

1274354

MED12
Mediator of RNA polymerase II transcription subunit 12

6

1

Small-scale

0.732

High

1347149

MED13
Mediator of RNA polymerase II transcription subunit 13

6

1

Small-scale

0.730

High

48735

MED19
Mediator of RNA polymerase II transcription subunit 19

8

0

Small-scale

0.722

High

1312767

MED18
Mediator of RNA polymerase II transcription subunit 18

7

0

Small-scale

0.720

High

206656

MED7
Mediator of RNA polymerase II transcription subunit 7

7

0

Small-scale

0.717

High

225424

MED14
Mediator of RNA polymerase II transcription subunit 14

5

1

Small-scale

0.712

High

1174781

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

5

1

Small-scale

0.712

High

1074731

MED22
Mediator of RNA polymerase II transcription subunit 22

6

0

Small-scale

0.705

High

1346436

MED17
Mediator of RNA polymerase II transcription subunit 17

6

0

Small-scale

0.705

High

313470

MED26
Mediator of RNA polymerase II transcription subunit 26

6

0

Small-scale

0.701

High

1312301

MED10
Mediator of RNA polymerase II transcription subunit 10

6

0

Small-scale

0.701

High

1334003

MED20
Mediator of RNA polymerase II transcription subunit 20

6

0

Small-scale

0.701

High

624519

CCNC
Cyclin-C

4

1

High-throughput

0.694

High

1347145

MED29
Mediator of RNA polymerase II transcription subunit 29

5

0

Small-scale

0.691

High

1291850

MED8
Mediator of RNA polymerase II transcription subunit 8

5

0

Small-scale

0.688

High

1328954

MED28
Mediator of RNA polymerase II transcription subunit 28

5

0

High-throughput

0.688

High

265368

MED24
Mediator of RNA polymerase II transcription subunit 24

5

0

Small-scale

0.686

High

270536

MED6
Mediator of RNA polymerase II transcription subunit 6

5

0

Small-scale

0.682

High

583822

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

4

0

High-throughput

0.670

High

1347147

MED11
Mediator of RNA polymerase II transcription subunit 11

4

0

Small-scale

0.670

High

1293706

MED30
Mediator of RNA polymerase II transcription subunit 30

4

0

Small-scale

0.667

High

1347159

MED31
Mediator of RNA polymerase II transcription subunit 31

4

0

Small-scale

0.667

High

625068

RPB1
DNA-directed RNA polymerase II subunit RPB1

4

0

High-throughput

0.664

High

677030

RPB2
DNA-directed RNA polymerase II subunit RPB2

4

0

High-throughput

0.664

High

1301095

MED15
Mediator of RNA polymerase II transcription subunit 15

4

0

High-throughput

0.664

High

1158927

MED27
Mediator of RNA polymerase II transcription subunit 27

4

0

Small-scale

0.661

High

1347151

MED23
Mediator of RNA polymerase II transcription subunit 23

4

0

Small-scale

0.661

High

1347157

MED16
Mediator of RNA polymerase II transcription subunit 16

4

0

Small-scale

0.661

High

583604

RPB3
DNA-directed RNA polymerase II subunit RPB3

3

0

High-throughput

0.638

High

913967

RPB7
DNA-directed RNA polymerase II subunit RPB7

3

0

High-throughput

0.638

High

1174969

MED25
Mediator of RNA polymerase II transcription subunit 25

3

0

Small-scale

0.634

High

1206163

MD12L
Mediator of RNA polymerase II transcription subunit 12-like protein

2

1

High-throughput

0.611

High

181471

RPB4
DNA-directed RNA polymerase II subunit RPB4

2

0

High-throughput

0.602

High

854484

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

2

0

High-throughput

0.585

High

751857

GRP75
Stress-70 protein, mitochondrial

2

2

High-throughput

0.571

High

854381

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

2

0

High-throughput

0.559

High

1221377

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

2

0

High-throughput

0.559

High

131520

IMA4
Importin subunit alpha-4

1

1

High-throughput

0.536

High

1347144

MED9
Mediator of RNA polymerase II transcription subunit 9

2

0

Small-scale

0.528

High

295684

RMP
Unconventional prefoldin RPB5 interactor 1

1

0

High-throughput

0.513

High

865004

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.513

High

897646

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.513

High

959980

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.513

High

1087440

H2B2E
Histone H2B type 2-E

1

0

High-throughput

0.513

High

1157388

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

0

High-throughput

0.513

High

1198580

TAD2B
Transcriptional adapter 2-beta

1

0

High-throughput

0.513

High

1204104

CARM1
Histone-arginine methyltransferase CARM1

1

0

High-throughput

0.513

High

1257279

ZN384
Zinc finger protein 384

1

0

High-throughput

0.513

High

1287887

REPS1
RalBP1-associated Eps domain-containing protein 1

1

0

High-throughput

0.513

High

1335540

TAF9B
Transcription initiation factor TFIID subunit 9B

1

0

High-throughput

0.513

High

1347160

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

High-throughput

0.513

High

476459

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

High-throughput

0.501

High

229742

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

1

1

High-throughput

0.489

High

504846

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

717381

CTNB1
Catenin beta-1

1

2

High-throughput

0.479

High

924189

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

1

High-throughput

0.479

High

1078683

SMAD2
Mothers against decapentaplegic homolog 2

1

1

Small-scale

0.479

High

1078765

SMAD1
Mothers against decapentaplegic homolog 1

1

1

Small-scale

0.479

High

245010

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

370553

ESR1
Estrogen receptor

1

0

Small-scale

0.458

High

391476

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

0

High-throughput

0.458

High

434036

LYN
Tyrosine-protein kinase Lyn

1

0

High-throughput

0.458

High

518781

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

0

High-throughput

0.458

High

643608

PTBP1
Polypyrimidine tract-binding protein 1

1

0

High-throughput

0.458

High

725256

MYH10
Myosin-10

1

0

High-throughput

0.458

High

738897

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

0

High-throughput

0.458

High

898513

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.458

High

918028

H4
Histone H4

1

0

High-throughput

0.458

High

923560

RL8
Large ribosomal subunit protein uL2

1

0

High-throughput

0.458

High

1019147

TP53B
TP53-binding protein 1

1

0

High-throughput

0.458

High

1054619

RBM39
RNA-binding protein 39

1

0

High-throughput

0.458

High

1132751

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

0

High-throughput

0.458

High

1173773

ACD11
Acyl-CoA dehydrogenase family member 11

1

0

High-throughput

0.458

High

1281423

FBXW7
F-box/WD repeat-containing protein 7

1

0

Small-scale

0.458

High

1332185

STN1
CST complex subunit STN1

1

0

High-throughput

0.458

High

1347154

RUVB1
RuvB-like 1

1

0

High-throughput

0.458

High

73046

B4DUB1
cDNA FLJ50029, highly similar to Cell division cycle 2-like protein kinase 6

1

2

High-throughput

0.445

High

91314

E5RFK5
Cyclin-C

1

1

High-throughput

0.445

High

475208

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

2

High-throughput

0.445

High

714082

HS71L
Heat shock 70 kDa protein 1-like

1

1

High-throughput

0.445

High

843412

TCPD
T-complex protein 1 subunit delta

1

1

High-throughput

0.445

High

853494

IMA1
Importin subunit alpha-1

1

1

High-throughput

0.445

High

1061271

NUMA1
Nuclear mitotic apparatus protein 1

1

1

High-throughput

0.445

High

165583

SR140
U2 snRNP-associated SURP motif-containing protein

1

0

High-throughput

0.426

High

418719

NPM
Nucleophosmin

1

0

High-throughput

0.426

High

785725

LAP2A
Lamina-associated polypeptide 2, isoform alpha

1

0

High-throughput

0.426

High

855563

MSH6
DNA mismatch repair protein Msh6

1

0

High-throughput

0.426

High

912390

SMD1
Small nuclear ribonucleoprotein Sm D1

1

0

High-throughput

0.426

High

932893

EF1A1
Elongation factor 1-alpha 1

1

0

High-throughput

0.426

High

1069809

NONO
Non-POU domain-containing octamer-binding protein

1

0

High-throughput

0.426

High

1084913

SMN
Survival motor neuron protein

1

0

High-throughput

0.426

High

1347148

HDAC6
Histone deacetylase 6

1

0

High-throughput

0.426

High

1347153

DICER
Endoribonuclease Dicer

1

0

High-throughput

0.426

High

1347156

DDX52
Probable ATP-dependent RNA helicase DDX52

1

0

High-throughput

0.426

High

1347158

NOP58
Nucleolar protein 58

1

0

High-throughput

0.426

High

826913

TCPG
T-complex protein 1 subunit gamma

1

1

High-throughput

0.407

High

1347150

GPN3
GPN-loop GTPase 3

2

0

High-throughput

0.313

High

329051

TCL1B
T-cell leukemia/lymphoma protein 1B

1

0

High-throughput

0.279

Low

423371

PDIA1
Protein disulfide-isomerase

1

0

High-throughput

0.279

Low

532234

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.279

Low

1269080

NEUG
Neurogranin

1

0

High-throughput

0.279

Low

1347152

STX8
Syntaxin-8

1

0

High-throughput

0.269

Low

395902

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.261

Low

361615

APOA2
Apolipoprotein A-II

1

0

High-throughput

0.249

Low

534224

CD59
CD59 glycoprotein

1

0

High-throughput

0.249

Low

921064

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

0

High-throughput

0.249

Low

1150707

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

1

0

High-throughput

0.249

Low

1347146

TMOD3
Tropomodulin-3

1

0

High-throughput

0.249

Low

1347155

PKHA6
Pleckstrin homology domain-containing family A member 6

1

0

High-throughput

0.249

Low

324075

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.232

Low

500156

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.232

Low

892919

IF4A1
Eukaryotic initiation factor 4A-I

1

0

High-throughput

0.232

Low

946620

DCD
Dermcidin

1

0

High-throughput

0.232

Low

1268266

GCN1
Stalled ribosome sensor GCN1

1

0

High-throughput

0.232

Low

1346586

TMLH
Trimethyllysine dioxygenase, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024