Protein: LCLT1
Lysocardiolipin acyltransferase 1 (EC 2.3.1.-) (1-acylglycerol-3-phosphate O-acyltransferase 8) (1-AGP acyltransferase 8) (1-AGPAT 8) (EC 2.3.1.51) (Acyl-CoA:lysocardiolipin acyltransferase 1)

Gene: LCLT1, LCLAT1
Organism: Homo sapiens
Interactions: 179
UniProt ID: Q6UWP7

Gene Ontology (top 5):
GO:0003841 - 1-acylglycerol-3-phosphate O-acyltransferase activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0006654 - phosphatidic acid biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1248623

AGRG5
Adhesion G-protein coupled receptor G5

3

1

High-throughput

0.662

High

1248618

PRRT2
Proline-rich transmembrane protein 2

4

0

High-throughput

0.661

High

1248619

RETR3
Reticulophagy regulator 3

2

1

High-throughput

0.611

High

967313

TSN5
Tetraspanin-5

3

16

High-throughput

0.609

High

58670

FRMD3
FERM domain-containing protein 3

2

0

High-throughput

0.602

High

1248613

DLK2
Protein delta homolog 2

2

0

High-throughput

0.602

High

1248640

S39A7
Zinc transporter SLC39A7

2

13

High-throughput

0.601

High

130137

PGRC1
Membrane-associated progesterone receptor component 1

2

0

High-throughput

0.585

High

1248675

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

595067

KCNA2
Potassium voltage-gated channel subfamily A member 2

2

0

High-throughput

0.576

High

1248636

F174A
Membrane protein FAM174A

2

0

High-throughput

0.576

High

1248637

ADA32
Disintegrin and metalloproteinase domain-containing protein 32

2

3

High-throughput

0.574

High

1248690

ADA21
Disintegrin and metalloproteinase domain-containing protein 21

2

3

High-throughput

0.574

High

1248671

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

2

High-throughput

0.573

High

252606

TSN2
Tetraspanin-2

1

14

High-throughput

0.536

High

349456

TSN15
Tetraspanin-15

1

15

High-throughput

0.536

High

773545

COPB2
Coatomer subunit beta'

1

1

High-throughput

0.536

High

921929

COPA
Coatomer subunit alpha

1

1

High-throughput

0.536

High

1203698

TTMP
TPA-induced transmembrane protein

1

4

High-throughput

0.536

High

1238989

NIPA3
Magnesium transporter NIPA3

1

3

High-throughput

0.536

High

1248616

PCAT2
Lysophosphatidylcholine acyltransferase 2

1

2

High-throughput

0.536

High

1248644

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

2

High-throughput

0.536

High

1248661

UN93B
Protein unc-93 homolog B1

1

4

High-throughput

0.536

High

1248664

TTYH1
Protein tweety homolog 1

1

3

High-throughput

0.536

High

1248688

CLC2D
C-type lectin domain family 2 member D

1

7

High-throughput

0.536

High

1248689

ADA30
Disintegrin and metalloproteinase domain-containing protein 30

1

3

High-throughput

0.536

High

49744

TMM72
Transmembrane protein 72

1

0

High-throughput

0.513

High

158238

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.513

High

167162

T4S5
Transmembrane 4 L6 family member 5

1

0

High-throughput

0.513

High

583318

FOLR1
Folate receptor alpha

1

0

High-throughput

0.513

High

1180850

S4A8
Electroneutral sodium bicarbonate exchanger 1

1

0

High-throughput

0.513

High

1248666

DNJC5
DnaJ homolog subfamily C member 5

1

0

High-throughput

0.513

High

1248668

IPPK
Inositol-pentakisphosphate 2-kinase

1

0

High-throughput

0.513

High

1248684

TM63C
Osmosensitive cation channel TMEM63C

1

0

High-throughput

0.513

High

248477

O10H2
Olfactory receptor 10H2

1

1

High-throughput

0.489

High

477431

CD63
CD63 antigen

1

15

High-throughput

0.489

High

618393

TSN8
Tetraspanin-8

1

15

High-throughput

0.489

High

907023

CCR6
C-C chemokine receptor type 6

1

6

High-throughput

0.489

High

1032598

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

1

High-throughput

0.489

High

1057551

ACHD
Acetylcholine receptor subunit delta

1

2

High-throughput

0.489

High

1248627

M4A15
Membrane-spanning 4-domains subfamily A member 15

1

1

High-throughput

0.489

High

1248650

GPR21
Probable G-protein coupled receptor 21

1

4

High-throughput

0.489

High

1248651

ADAM2
Disintegrin and metalloproteinase domain-containing protein 2

1

3

High-throughput

0.489

High

1248652

ZNT2
Proton-coupled zinc antiporter SLC30A2

1

3

High-throughput

0.489

High

385867

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

High-throughput

0.479

High

414054

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

1229535

VIR
Protein virilizer homolog

1

2

High-throughput

0.479

High

1248611

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

242045

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

48666

ESYT2
Extended synaptotagmin-2

1

2

High-throughput

0.445

High

104346

F5H6I7
Atlastin GTPase 3

1

3

High-throughput

0.445

High

170821

CLGN
Calmegin

1

5

High-throughput

0.445

High

182609

GP182
G-protein coupled receptor 182

1

13

High-throughput

0.445

High

248892

GSDME
Gasdermin-E

1

1

High-throughput

0.445

High

256058

S19A2
Thiamine transporter 1

1

2

High-throughput

0.445

High

275528

RTN2
Reticulon-2

1

2

High-throughput

0.445

High

296515

STAM2
Signal transducing adapter molecule 2

1

1

High-throughput

0.445

High

328937

RTN3
Reticulon-3

1

2

High-throughput

0.445

High

333057

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

5

High-throughput

0.445

High

360020

NB5R3
NADH-cytochrome b5 reductase 3

1

2

High-throughput

0.445

High

535207

BIP
Endoplasmic reticulum chaperone BiP

1

6

High-throughput

0.445

High

565637

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

8

High-throughput

0.445

High

607939

ACHB2
Neuronal acetylcholine receptor subunit beta-2

1

2

High-throughput

0.445

High

697925

CALR
Calreticulin

1

5

High-throughput

0.445

High

698786

CALX
Calnexin

1

5

High-throughput

0.445

High

870248

S6A12
Sodium- and chloride-dependent betaine transporter

1

13

High-throughput

0.445

High

870366

S6A11
Sodium- and chloride-dependent GABA transporter 3

1

13

High-throughput

0.445

High

888902

TMEDA
Transmembrane emp24 domain-containing protein 10

1

2

High-throughput

0.445

High

903714

SSRD
Translocon-associated protein subunit delta

1

1

High-throughput

0.445

High

903965

BAP31
B-cell receptor-associated protein 31

1

2

High-throughput

0.445

High

964021

COPZ1
Coatomer subunit zeta-1

1

1

High-throughput

0.445

High

987079

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

1

High-throughput

0.445

High

1027052

REEP5
Receptor expression-enhancing protein 5

1

2

High-throughput

0.445

High

1053019

VMAT2
Synaptic vesicular amine transporter

1

2

High-throughput

0.445

High

1139463

S39AE
Metal cation symporter ZIP14

1

13

High-throughput

0.445

High

1146562

TMED2
Transmembrane emp24 domain-containing protein 2

1

2

High-throughput

0.445

High

1152803

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

1

High-throughput

0.445

High

1199194

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

9

High-throughput

0.445

High

1236189

MFSD5
Molybdate-anion transporter

1

1

High-throughput

0.445

High

1243612

S27A1
Long-chain fatty acid transport protein 1

1

2

High-throughput

0.445

High

1248622

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

4

High-throughput

0.445

High

1248626

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

1

High-throughput

0.445

High

1248630

DHB11
Estradiol 17-beta-dehydrogenase 11

1

10

High-throughput

0.445

High

1248633

ATLA2
Atlastin-2

1

3

High-throughput

0.445

High

1248639

ATLA1
Atlastin-1

1

3

High-throughput

0.445

High

1248642

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

2

High-throughput

0.445

High

1248645

S39AD
Zinc transporter ZIP13

1

13

High-throughput

0.445

High

1248646

SCYL1
N-terminal kinase-like protein

1

2

High-throughput

0.445

High

1248655

ESYT1
Extended synaptotagmin-1

1

2

High-throughput

0.445

High

1248660

METL9
Protein-L-histidine N-pros-methyltransferase

1

1

High-throughput

0.445

High

1248662

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

13

High-throughput

0.445

High

1248665

TMX1
Thioredoxin-related transmembrane protein 1

1

1

High-throughput

0.445

High

1248674

RTN4
Reticulon-4

1

2

High-throughput

0.445

High

1248676

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

2

High-throughput

0.445

High

1248680

SCN3B
Sodium channel regulatory subunit beta-3

1

3

High-throughput

0.445

High

1248682

TECR
Very-long-chain enoyl-CoA reductase

1

2

High-throughput

0.445

High

1248683

VAPA
Vesicle-associated membrane protein-associated protein A

1

5

High-throughput

0.445

High

1248686

COPG2
Coatomer subunit gamma-2

1

1

High-throughput

0.445

High

1248692

DHRS7
Dehydrogenase/reductase SDR family member 7

1

9

High-throughput

0.445

High

1248693

TMED5
Transmembrane emp24 domain-containing protein 5

1

2

High-throughput

0.445

High

1248695

COPG1
Coatomer subunit gamma-1

1

1

High-throughput

0.445

High

227595

SPOP
Speckle-type POZ protein

1

1

High-throughput

0.437

High

588970

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.437

High

695756

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.437

High

768477

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

1004734

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.437

High

1238714

TECT3
Tectonic-3

1

2

High-throughput

0.437

High

1248614

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.437

High

1248617

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

1248620

LYPD6
Ly6/PLAUR domain-containing protein 6

1

1

High-throughput

0.437

High

1248648

RING2
E3 ubiquitin-protein ligase RING2

1

1

High-throughput

0.437

High

1248667

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

1248677

OTULL
Inactive ubiquitin thioesterase OTULINL

1

1

High-throughput

0.437

High

1248687

ACHA9
Neuronal acetylcholine receptor subunit alpha-9

1

2

High-throughput

0.437

High

1248691

GPR52
G-protein coupled receptor 52

1

4

High-throughput

0.437

High

50591

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.426

High

60356

NBAS
NBAS subunit of NRZ tethering complex

1

0

High-throughput

0.426

High

211803

ZW10
Centromere/kinetochore protein zw10 homolog

1

0

High-throughput

0.426

High

213616

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

1

0

High-throughput

0.426

High

215584

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.426

High

283281

ERLN1
Erlin-1

1

0

High-throughput

0.426

High

462477

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

0

High-throughput

0.426

High

541032

PIM1
Serine/threonine-protein kinase pim-1

1

0

High-throughput

0.426

High

567009

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.426

High

873249

COPD
Coatomer subunit delta

1

0

High-throughput

0.426

High

876902

KC1A
Casein kinase I isoform alpha

1

0

High-throughput

0.426

High

883107

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

0

High-throughput

0.426

High

921695

COPB
Coatomer subunit beta

1

0

High-throughput

0.426

High

1009848

NUCB2
Nucleobindin-2

1

0

High-throughput

0.426

High

1093530

TRDN
Triadin

1

0

High-throughput

0.426

High

1096985

PRDX4
Peroxiredoxin-4

1

0

High-throughput

0.426

High

1131288

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.426

High

1136237

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.426

High

1139211

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

0

High-throughput

0.426

High

1139327

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

0

High-throughput

0.426

High

1145596

RCN1
Reticulocalbin-1

1

0

High-throughput

0.426

High

1147776

DHC24
Delta(24)-sterol reductase

1

0

High-throughput

0.426

High

1239225

ARMC6
Armadillo repeat-containing protein 6

1

0

High-throughput

0.426

High

1248615

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

0

High-throughput

0.426

High

1248621

S35F3
Solute carrier family 35 member F3

1

0

High-throughput

0.426

High

1248624

FXL16
F-box/LRR-repeat protein 16

1

0

High-throughput

0.426

High

1248628

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.426

High

1248631

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.426

High

1248632

VP37A
Vacuolar protein sorting-associated protein 37A

1

0

High-throughput

0.426

High

1248634

MCFD2
Multiple coagulation factor deficiency protein 2

1

0

High-throughput

0.426

High

1248638

SCFD1
Sec1 family domain-containing protein 1

1

0

High-throughput

0.426

High

1248643

ASTRA
Protein Aster-A

1

0

High-throughput

0.426

High

1248647

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

1248654

ERP44
Endoplasmic reticulum resident protein 44

1

0

High-throughput

0.426

High

1248656

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.426

High

1248657

WDR11
WD repeat-containing protein 11

1

0

High-throughput

0.426

High

1248658

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.426

High

1248659

RGAP1
Rac GTPase-activating protein 1

1

0

High-throughput

0.426

High

1248663

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

0

High-throughput

0.426

High

1248669

ZDH11
Palmitoyltransferase ZDHHC11

1

0

High-throughput

0.426

High

1248672

APMAP
Adipocyte plasma membrane-associated protein

1

0

High-throughput

0.426

High

1248678

TM38B
Trimeric intracellular cation channel type B

1

0

High-throughput

0.426

High

1248694

SERC
Phosphoserine aminotransferase

1

0

High-throughput

0.426

High

683264

TNR5
Tumor necrosis factor receptor superfamily member 5

1

1

High-throughput

0.407

High

886081

CXCR3
C-X-C chemokine receptor type 3

1

7

High-throughput

0.407

High

1015049

ARF5
ADP-ribosylation factor 5

1

2

High-throughput

0.407

High

1219494

ANR22
Ankyrin repeat domain-containing protein 22

1

1

High-throughput

0.407

High

1248625

SVOP
Synaptic vesicle 2-related protein

1

8

High-throughput

0.407

High

1248641

LPAR1
Lysophosphatidic acid receptor 1

1

6

High-throughput

0.407

High

1248649

S1PR3
Sphingosine 1-phosphate receptor 3

1

5

High-throughput

0.407

High

1248681

PSD3
PH and SEC7 domain-containing protein 3

1

1

High-throughput

0.407

High

1248635

LNX1
E3 ubiquitin-protein ligase LNX

1

0

High-throughput

0.299

High

615155

GBRG2
Gamma-aminobutyric acid receptor subunit gamma-2

1

0

High-throughput

0.279

Low

1195439

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

0

High-throughput

0.279

Low

1248612

IGFL3
Insulin growth factor-like family member 3

1

0

High-throughput

0.279

Low

1248629

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.279

Low

1248670

RXFP1
Relaxin receptor 1

1

0

High-throughput

0.279

Low

1248673

KCMB3
Calcium-activated potassium channel subunit beta-3

1

0

High-throughput

0.279

Low

1248685

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

0

High-throughput

0.279

Low

1231715

PVRIG
Transmembrane protein PVRIG

1

0

High-throughput

0.249

Low

318994

MICA2
[F-actin]-monooxygenase MICAL2

1

0

High-throughput

0.232

Low

1153398

CD226
CD226 antigen

1

0

High-throughput

0.232

Low

1248653

PXL2A
Peroxiredoxin-like 2A

1

0

High-throughput

0.232

Low

1248679

GPTC2
G patch domain-containing protein 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025