HitPredict

Interactor 1: AP3B1 (O00203)
AP-3 complex subunit beta-1 (Adaptor protein complex AP-3 subunit beta-1) (Adaptor-related protein complex 3 subunit beta-1) (Beta-3A-adaptin) (Clathrin assembly protein complex 3 beta-1 large chain)
Gene: AP3B1

Interactor 2: LMTK1 (Q6ZMQ8)
Serine/threonine-protein kinase LMTK1 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (Lemur tyrosine kinase 1) (p35-binding protein) (p35BP)
Gene: AATK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1094 Hs			1 1374
+	Hs
		925919 AP2B1_HUMAN (33-744): 0: 558: 25.14		LMTK1_HUMAN (1-1374): 0: 976: 100.00
+	Hs
		1014036 AP1B1_HUMAN (33-725): 2.94e-176: 542: 25.56		LMTK1_HUMAN (1-1374): 0: 976: 100.00
+	Hs
		321578 AP2A1_HUMAN (42-648): 1.93e-154: 486: 14.02		LMTK1_HUMAN (1-1374): 0: 976: 100.00
+	Hs
		119906 AP3B1_HUMAN (1-1094): 0: 989: 100.00		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		119936 AP3B1_HUMAN (1-1094): 0: 989: 100.00		BMX_HUMAN (119-391): 1.16e-32: 138: 32.12
+	Hs
		384781 AP3B2_HUMAN (3-1093): 0: 849: 59.69		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		507940 AP2B1_HUMAN (33-744): 0: 558: 25.14		FGFR1_HUMAN (28-460): 6.26e-120: 396: 21.00
+	Hs
		1014018 AP1B1_HUMAN (33-725): 2.94e-176: 542: 25.56		NTRK2_HUMAN (30-400): 4.89e-106: 357: 27.78
+	Hs
		321487 AP2A1_HUMAN (42-648): 1.93e-154: 486: 14.02		FGFR3_HUMAN (29-448): 5.82e-123: 403: 23.42
+	Hs
		321475 AP2A1_HUMAN (42-648): 1.93e-154: 486: 14.02		FGFR1_HUMAN (28-460): 6.26e-120: 396: 21.00
+	Hs
		321464 AP2A1_HUMAN (42-648): 1.93e-154: 486: 14.02		LCK_HUMAN (98-410): 1.51e-107: 352: 24.20
+	Rn
		71352 B2RYN6_RAT (16-830): 0: 581: 13.00		INSR_RAT (111-395): 8.57e-39: 160: 35.25
+	Hs
		212583 AP1G1_HUMAN (16-830): 0: 579: 13.12		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		384621 AP2B1_HUMAN (33-744): 0: 558: 25.14		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Rn
		102587 G3V9N8_RAT (33-724): 6.52e-173: 534: 25.18		INSR_RAT (111-395): 8.57e-39: 160: 35.25
+	Hs
		384728 AP1B1_HUMAN (33-725): 2.94e-176: 542: 25.56		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		321460 AP2A1_HUMAN (42-648): 1.93e-154: 486: 14.02		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		337419 AP2B1_HUMAN (33-744): 0: 558: 25.14		ABL1_HUMAN (588-1118): 4.91e-10: 66.4: 13.32
+	Hs
		302086 AP2A2_HUMAN (42-660): 3.11e-152: 479: 12.87		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		321450 AP2A1_HUMAN (42-648): 1.93e-154: 486: 14.02		ABL1_HUMAN (588-1118): 4.91e-10: 66.4: 13.32