HitPredict

Interactor 1: STK4 (Q13043)
Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]
Gene: STK4

Interactor 2: RB6I2 (Q8IUD2)
ELKS/Rab6-interacting/CAST family member 1 (ERC-1) (Rab6-interacting protein 2)
Gene: ERC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	23455922
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 487 Hs			1 1116
+	Hs
		682193 AKT2_HUMAN (3-353): 1.95e-134: 398: 21.88		RB6I2_HUMAN (1-1116): 2.23e-82: 293: 100.00
+	Hs
		522545 STK4_HUMAN (1-487): 7.89e-170: 489: 100.00		MYH1_HUMAN (390-1116): 2.17e-34: 146: 13.62
+	Hs
		1023138 STK4_HUMAN (1-487): 7.89e-170: 489: 100.00		MYH13_HUMAN (1-745): 5.53e-31: 134: 9.88
+	Hs
		528369 STK4_HUMAN (1-487): 7.89e-170: 489: 100.00		MYH6_HUMAN (3-544): 6.64e-24: 111: 9.47
+	Hs
		1023137 STK4_HUMAN (1-487): 7.89e-170: 489: 100.00		MYH2_HUMAN (3-612): 1.73e-23: 110: 9.34
+	Hs
		528408 STK4_HUMAN (1-487): 7.89e-170: 489: 100.00		MYH8_HUMAN (3-541): 4.07e-23: 109: 10.26
+	Hs
		522609 STK4_HUMAN (1-487): 7.89e-170: 489: 100.00		MYH7_HUMAN (6-513): 7.72e-21: 101: 9.84
+	Hs
		502911 STK4_HUMAN (1-487): 7.89e-170: 489: 100.00		MYH3_HUMAN (4-532): 1.56e-20: 100: 10.40
+	Hs
		522546 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		MYH1_HUMAN (390-1116): 2.17e-34: 146: 13.62
+	Hs
		1027453 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		MYH13_HUMAN (1-745): 5.53e-31: 134: 9.88
+	Hs
		528371 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		MYH6_HUMAN (3-544): 6.64e-24: 111: 9.47
+	Hs
		1027452 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		MYH2_HUMAN (3-612): 1.73e-23: 110: 9.34
+	Hs
		528409 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		MYH8_HUMAN (3-541): 4.07e-23: 109: 10.26
+	Hs
		522610 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		MYH7_HUMAN (6-513): 7.72e-21: 101: 9.84
+	Hs
		502912 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		MYH3_HUMAN (4-532): 1.56e-20: 100: 10.40
+	Hs
		522538 KAPCB_HUMAN (14-319): 8.38e-123: 364: 25.63		MYH1_HUMAN (390-1116): 2.17e-34: 146: 13.62
+	Hs
		528359 KAPCB_HUMAN (14-319): 8.38e-123: 364: 25.63		MYH6_HUMAN (3-544): 6.64e-24: 111: 9.47
+	Hs
		610795 KAPCB_HUMAN (14-319): 8.38e-123: 364: 25.63		MYH2_HUMAN (3-612): 1.73e-23: 110: 9.34
+	Ce
		219385 CST1_CAEEL (3-484): 9.71e-137: 405: 50.00		O44490_CAEEL (161-834): 3.6e-09: 63.2: 20.15
+	Ce
		110169 GCK1_CAEEL (1-369): 1.94e-128: 389: 44.76		O44490_CAEEL (161-834): 3.6e-09: 63.2: 20.15