Interactor 1: TLR4 (O00206)
Toll-like receptor 4 (hToll) (CD antigen CD284)
Gene: TLR4
Interactor 2: IRAK4 (Q9NWZ3)
Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)
Gene: IRAK4
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.62 | 1.00 | 0.789 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | LRR_4~PK_Tyr_Ser-Thr, LRR_8~PK_Tyr_Ser-Thr |
| Common GO terms | GO:0002224 - toll-like receptor signaling pathway GO:0002755 - MyD88-dependent toll-like receptor signaling pathway GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0007254 - JNK cascade and 7 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
