Protein: GPSM1
G-protein-signaling modulator 1 (Activator of G-protein signaling 3)

Gene: GPSM1
Organism: Homo sapiens
Interactions: 57
UniProt ID: Q86YR5

Gene Ontology (top 5):
GO:0000132 - establishment of mitotic spindle orientation
GO:0000139 - Golgi membrane
GO:0001965 - G-protein alpha-subunit binding
GO:0005092 - GDP-dissociation inhibitor activity
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

475990

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

6

15

Small-scale

0.952

High

989851

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

4

15

Small-scale

0.899

High

1295359

GPSM1
G-protein-signaling modulator 1

1

15

High-throughput

0.698

High

1113609

CUL3
Cullin-3

1

12

High-throughput

0.691

High

1169072

INSC
Protein inscuteable homolog

1

3

High-throughput

0.691

High

1134634

NUMA1
Nuclear mitotic apparatus protein 1

3

7

High-throughput

0.667

High

1204753

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

3

3

Small-scale

0.656

High

1164197

UGPA
UTP--glucose-1-phosphate uridylyltransferase

3

0

High-throughput

0.638

High

1288076

SAPC2
Suppressor APC domain-containing protein 2

3

0

High-throughput

0.638

High

1295372

WDR83
WD repeat domain-containing protein 83

4

10

High-throughput

0.630

High

260146

BRD4
Bromodomain-containing protein 4

3

6

High-throughput

0.609

High

1218927

TASO2
Protein TASOR 2

2

6

High-throughput

0.606

High

1295379

DACH1
Dachshund homolog 1

2

0

High-throughput

0.602

High

242189

PRKN
E3 ubiquitin-protein ligase parkin

2

15

High-throughput

0.584

High

1295375

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

3

Small-scale

0.578

High

1208147

CD158
Coiled-coil domain-containing protein 158

2

4

High-throughput

0.577

High

1295367

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

11

Small-scale

0.561

High

320829

KLH18
Kelch-like protein 18

2

3

High-throughput

0.558

High

288308

GCM2
Chorion-specific transcription factor GCMb

2

1

High-throughput

0.553

High

1120678

VEZF1
Vascular endothelial zinc finger 1

2

7

High-throughput

0.553

High

1289415

FA83A
Protein FAM83A

2

1

High-throughput

0.553

High

1295362

DCA11
DDB1- and CUL4-associated factor 11

2

15

High-throughput

0.553

High

1295365

SEPT1
Septin-1

2

4

High-throughput

0.553

High

1295370

F161B
Protein FAM161B

2

1

High-throughput

0.553

High

1295373

GLIS2
Zinc finger protein GLIS2

2

7

High-throughput

0.553

High

1295377

HM20A
High mobility group protein 20A

2

14

High-throughput

0.553

High

1295378

DMRT3
Doublesex- and mab-3-related transcription factor 3

2

1

High-throughput

0.553

High

900403

FXR2
RNA-binding protein FXR2

1

7

High-throughput

0.541

High

1277174

POGZ
Pogo transposable element with ZNF domain

1

1

High-throughput

0.536

High

1295368

EFMT3
EEF1A lysine methyltransferase 3

1

6

High-throughput

0.536

High

1224995

KANK2
KN motif and ankyrin repeat domain-containing protein 2

1

8

High-throughput

0.523

High

1139075

DAZP2
DAZ-associated protein 2

1

0

High-throughput

0.518

High

1295366

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.513

High

354235

ZBED1
E3 SUMO-protein ligase ZBED1

1

1

High-throughput

0.494

High

1151007

PCH2
Pachytene checkpoint protein 2 homolog

1

12

High-throughput

0.494

High

1295361

USBP1
Harmonin-binding protein USHBP1

1

4

High-throughput

0.494

High

1295374

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

1

1

High-throughput

0.494

High

1295369

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

1

10

High-throughput

0.489

High

1295371

NPAS1
Neuronal PAS domain-containing protein 1

1

4

High-throughput

0.489

High

1292387

OSTM1
Osteopetrosis-associated transmembrane protein 1

1

0

Small-scale

0.480

High

58733

PTPC1
Protein tyrosine phosphatase domain-containing protein 1

1

7

High-throughput

0.479

High

173027

XPO1
Exportin-1

1

11

High-throughput

0.479

High

412208

NTRK1
High affinity nerve growth factor receptor

1

11

High-throughput

0.479

High

530042

TAU
Microtubule-associated protein tau

1

13

High-throughput

0.479

High

648576

FGFR4
Fibroblast growth factor receptor 4

1

12

High-throughput

0.479

High

771904

CBS
Cystathionine beta-synthase

1

3

Small-scale

0.479

High

1145887

RBP1
RalA-binding protein 1

1

7

Small-scale

0.479

High

1224848

TENS2
Tensin-2

1

10

High-throughput

0.479

High

1295376

PKHA4
Pleckstrin homology domain-containing family A member 4

1

17

High-throughput

0.479

High

783318

TRI23
E3 ubiquitin-protein ligase TRIM23

1

0

Small-scale

0.458

High

1254499

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.437

High

1295363

G6PT3
Glucose-6-phosphate exchanger SLC37A2

1

0

High-throughput

0.426

High

155002

BHE40
Class E basic helix-loop-helix protein 40

2

0

High-throughput

0.316

High

1295056

F90A1
Protein FAM90A1

2

0

High-throughput

0.316

High

1295360

RIBC1
RIB43A-like with coiled-coils protein 1

2

0

High-throughput

0.316

High

1295364

TEKT4
Tektin-4

2

0

High-throughput

0.316

High


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Last updated: 11Aug2025