HitPredict

Interactor 1: CHFR (Q5FWP4)
E3 ubiquitin-protein ligase CHFR (EC 2.3.2.27) (Checkpoint with forkhead and RING finger domains protein) (RING-type E3 ubiquitin transferase CHFR)
Gene: CHFR

Interactor 2: TBB5 (Q91575)
Tubulin beta chain (Tubulin beta-5 chain)
Gene: tubb

Species: Xenopus laevis

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	18504434
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 625 Xl			1 444
+	Hs
		765480 BMI1_HUMAN (249-420): 8.39e-41: 153: 17.33		TBB3_HUMAN (1-444): 0: 715: 92.57
+	Hs
		457261 BMI1_HUMAN (249-420): 8.39e-41: 153: 17.33		TBB5_HUMAN (1-429): 0: 710: 100.00
+	Hs
		765368 BMI1_HUMAN (249-420): 8.39e-41: 153: 17.33		TBB4B_HUMAN (1-427): 0: 709: 98.36
+	Hs
		765845 BMI1_HUMAN (249-420): 8.39e-41: 153: 17.33		TBB6_HUMAN (1-432): 0: 705: 92.13
+	Hs
		457568 COP1_HUMAN (180-462): 2.23e-33: 138: 13.78		TBB5_HUMAN (1-429): 0: 710: 100.00
+	Hs
		997435 COP1_HUMAN (180-462): 2.23e-33: 138: 13.78		TBB4B_HUMAN (1-427): 0: 709: 98.36
+	Hs
		1340801 COP1_HUMAN (180-462): 2.23e-33: 138: 13.78		TBB2B_HUMAN (1-430): 0: 708: 97.44
+	Hs
		1340800 COP1_HUMAN (180-462): 2.23e-33: 138: 13.78		TBB6_HUMAN (1-432): 0: 705: 92.13
+	Hs
		1191901 COP1_HUMAN (180-462): 2.23e-33: 138: 13.78		TBB8_HUMAN (1-427): 0: 701: 89.70
+	Hs
		997474 RING2_HUMAN (241-436): 2.14e-30: 123: 16.50		TBB4B_HUMAN (1-427): 0: 709: 98.36
+	Hs
		1118567 RING2_HUMAN (241-436): 2.14e-30: 123: 16.50		TBB2A_HUMAN (1-430): 0: 705: 96.98
+	Hs
		302329 RNF8_HUMAN (258-347): 1e-25: 113: 27.78		TBB5_HUMAN (1-429): 0: 710: 100.00
+	Hs
		302474 RNF8_HUMAN (258-347): 1e-25: 113: 27.78		TBB4B_HUMAN (1-427): 0: 709: 98.36