HitPredict

Interactor 1: FRAS1 (Q86XX4)
Extracellular matrix organizing protein FRAS1 (Fraser syndrome 1 protein)
Gene: FRAS1

Interactor 2: PSG8 (Q9UQ74)
Pregnancy-specific beta-1-glycoprotein 8 (PS-beta-G-8) (PSBG-8) (Pregnancy-specific glycoprotein 8)
Gene: PSG8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 4008 Hs			1 426
+	Hs
		685264 FRAS1_HUMAN (1-4008): 0: 2806: 100.00		CEAM8_HUMAN (122-426): 5.47e-45: 161: 39.63
+	Hs
		1132304 FREM2_HUMAN (1296-3338): 2.12e-108: 393: 18.62		PSG8_HUMAN (1-426): 1.75e-103: 315: 100.00
+	Hs
		685251 FREM2_HUMAN (1296-3338): 2.12e-108: 393: 18.62		CEAM8_HUMAN (122-426): 5.47e-45: 161: 39.63
+	Hs
		1263696 AGRV1_HUMAN (1121-3205): 1.27e-35: 153: 12.28		PSG8_HUMAN (1-426): 1.75e-103: 315: 100.00
+	Hs
		1055023 FAT1_HUMAN (208-422): 2.76e-12: 75.8: 10.19		PSG8_HUMAN (1-426): 1.75e-103: 315: 100.00
+	Hs
		1336515 CELR2_HUMAN (985-1093): 1.37e-10: 70.4: 16.36		PSG8_HUMAN (1-426): 1.75e-103: 315: 100.00
+	Hs
		1167041 FAT4_HUMAN (2-88): 4.91e-10: 68.5: 9.89		PSG8_HUMAN (1-426): 1.75e-103: 315: 100.00
+	Hs
		685278 AGRV1_HUMAN (1121-3205): 1.27e-35: 153: 12.28		CEAM8_HUMAN (122-426): 5.47e-45: 161: 39.63
+	Hs
		980365 NOTC2_HUMAN (567-1139): 7.18e-39: 163: 13.53		CNTN1_HUMAN (1-424): 1.01e-35: 141: 12.10
+	Hs
		804225 NOTC1_HUMAN (5-694): 7.39e-38: 160: 13.02		CNTN1_HUMAN (1-424): 1.01e-35: 141: 12.10
+	Hs
		604220 TENX_HUMAN (2-331): 6.19e-25: 117: 15.77		CEAM6_HUMAN (122-426): 1.89e-49: 173: 39.69
+	Hs
		993887 PCDH1_HUMAN (2678-3411): 7.66e-49: 194: 10.88		CEA21_HUMAN (252-426): 3.13e-20: 92.1: 16.75
+	Hs
		685280 PCSK5_HUMAN (847-1155): 3.35e-26: 121: 22.75		CEAM8_HUMAN (122-426): 5.47e-45: 161: 39.63
+	Hs
		980481 NOTC2_HUMAN (567-1139): 7.18e-39: 163: 13.53		PXDN_HUMAN (1-158): 3.51e-16: 83: 13.92
+	Hs
		685240 FAT1_HUMAN (208-422): 2.76e-12: 75.8: 10.19		CEAM8_HUMAN (122-426): 5.47e-45: 161: 39.63
+	Hs
		685259 FAT4_HUMAN (2-88): 4.91e-10: 68.5: 9.89		CEAM8_HUMAN (122-426): 5.47e-45: 161: 39.63
+	Hs
		685294 CELR3_HUMAN (988-1110): 8.39e-10: 67.8: 14.63		CEAM8_HUMAN (122-426): 5.47e-45: 161: 39.63
+	Hs
		1108811 CELR2_HUMAN (985-1093): 1.37e-10: 70.4: 16.36		CEA21_HUMAN (252-426): 3.13e-20: 92.1: 16.75
+	Hs
		1108786 FAT4_HUMAN (2-88): 4.91e-10: 68.5: 9.89		CEA21_HUMAN (252-426): 3.13e-20: 92.1: 16.75
+	Hs
		509884 CELR3_HUMAN (988-1110): 8.39e-10: 67.8: 14.63		PSG1_HUMAN (4-242): 8.38e-19: 90: 17.43