Protein: MTX1
Metaxin-1 (Mitochondrial outer membrane import complex protein 1)

Gene: MTX1
Organism: Homo sapiens
Interactions: 102
UniProt ID: Q13505

Gene Ontology (top 5):
GO:0001401 - SAM complex
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0007005 - mitochondrion organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1108474

SAM50
Sorting and assembly machinery component 50 homolog

2

5

Small-scale

0.806

High

669189

EDNRA
Endothelin-1 receptor

3

8

High-throughput

0.667

High

1108466

S39A9
Zinc transporter ZIP9

3

2

High-throughput

0.662

High

354333

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

4

Small-scale

0.647

High

1108430

KCIP4
Kv channel-interacting protein 4

3

0

High-throughput

0.638

High

854528

S15A1
Solute carrier family 15 member 1

2

1

High-throughput

0.628

High

1108440

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

2

1

High-throughput

0.628

High

1107682

SQSTM
Sequestosome-1

2

2

Small-scale

0.624

High

281587

MTX2
Metaxin-2

1

8

Small-scale

0.618

High

1108459

GHITM
Growth hormone-inducible transmembrane protein

2

1

High-throughput

0.612

High

1108441

TM171
Transmembrane protein 171

2

1

High-throughput

0.611

High

1108470

CCG4
Voltage-dependent calcium channel gamma-4 subunit

3

1

High-throughput

0.609

High

1108442

GLMP
Glycosylated lysosomal membrane protein

2

0

High-throughput

0.602

High

182526

GP182
G-protein coupled receptor 182

2

9

High-throughput

0.601

High

1052987

VMAT2
Synaptic vesicular amine transporter

2

2

High-throughput

0.601

High

1108468

OCAD1
OCIA domain-containing protein 1

2

2

High-throughput

0.584

High

406882

MAS
Proto-oncogene Mas

2

9

High-throughput

0.574

High

702772

5HT2C
5-hydroxytryptamine receptor 2C

2

1

High-throughput

0.574

High

771118

APJ
Apelin receptor

2

6

High-throughput

0.574

High

835270

VIPR2
Vasoactive intestinal polypeptide receptor 2

2

4

High-throughput

0.574

High

1108427

S39AC
Zinc transporter ZIP12

2

2

High-throughput

0.574

High

1108455

LPAR4
Lysophosphatidic acid receptor 4

2

8

High-throughput

0.574

High

774336

BASI
Basigin

2

0

High-throughput

0.559

High

627525

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

2

1

High-throughput

0.558

High

1108457

MLP3C
Microtubule-associated protein 1 light chain 3 gamma

2

3

Small-scale

0.543

High

638410

FPR1
fMet-Leu-Phe receptor

1

7

High-throughput

0.536

High

867614

GPR12
G-protein coupled receptor 12

1

5

High-throughput

0.536

High

867959

GLR
Glucagon receptor

1

4

High-throughput

0.536

High

1042741

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

1

4

High-throughput

0.536

High

1108439

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

1

High-throughput

0.536

High

1108443

AQP3
Aquaporin-3

1

2

High-throughput

0.536

High

1108467

DJC11
DnaJ homolog subfamily C member 11

1

5

High-throughput

0.536

High

1108473

SC5A6
Sodium-dependent multivitamin transporter

1

2

High-throughput

0.536

High

1108464

LFG4
Protein lifeguard 4

1

1

High-throughput

0.515

High

520834

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

0

High-throughput

0.513

High

1108452

RUSF1
RUS family member 1

1

0

High-throughput

0.513

High

1108456

S26A6
Solute carrier family 26 member 6

1

0

High-throughput

0.513

High

1108458

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

3

Small-scale

0.501

High

133247

P2Y10
Putative P2Y purinoceptor 10

1

9

High-throughput

0.489

High

165939

FFAR1
Free fatty acid receptor 1

1

8

High-throughput

0.489

High

210389

MTLR
Motilin receptor

1

5

High-throughput

0.489

High

221453

OX2R
Orexin receptor type 2

1

2

High-throughput

0.489

High

832400

OPRX
Nociceptin receptor

1

4

High-throughput

0.489

High

848481

MAGA8
Melanoma-associated antigen 8

1

1

High-throughput

0.489

High

880136

PTH2R
Parathyroid hormone 2 receptor

1

4

High-throughput

0.489

High

1108426

MICB
MHC class I polypeptide-related sequence B

1

1

High-throughput

0.489

High

1108451

BSCL2
Seipin

1

1

High-throughput

0.489

High

1108475

GPR45
Probable G-protein coupled receptor 45

1

5

High-throughput

0.489

High

216685

HTRA2
Serine protease HTRA2, mitochondrial

1

1

High-throughput

0.479

High

245463

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

2

High-throughput

0.479

High

348494

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

4

High-throughput

0.479

High

897262

CDK7
Cyclin-dependent kinase 7

1

1

High-throughput

0.479

High

1004530

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.479

High

1108423

SURF1
Surfeit locus protein 1

1

1

High-throughput

0.479

High

1108424

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

1

High-throughput

0.479

High

1108428

MIC10
MICOS complex subunit MIC10

1

1

Small-scale

0.479

High

1108429

MIC13
MICOS complex subunit MIC13

1

1

High-throughput

0.479

High

1108433

MIC27
MICOS complex subunit MIC27

1

4

High-throughput

0.479

High

1108445

AKAP1
A-kinase anchor protein 1, mitochondrial

1

4

High-throughput

0.479

High

1108446

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

1108448

S2546
Mitochondrial outer membrane protein SLC25A46

1

1

Small-scale

0.479

High

1108449

OPTN
Optineurin

1

2

High-throughput

0.479

High

1108450

OMA1
Metalloendopeptidase OMA1, mitochondrial

1

1

High-throughput

0.479

High

1108454

PHB2
Prohibitin-2

1

4

High-throughput

0.479

High

1108461

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

1108463

SFXN1
Sideroflexin-1

1

2

High-throughput

0.479

High

1108465

DBLOH
Diablo IAP-binding mitochondrial protein

1

2

High-throughput

0.479

High

1108472

UBQL2
Ubiquilin-2

1

2

High-throughput

0.479

High

1108471

CLN8
Protein CLN8

1

0

Small-scale

0.460

High

275017

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

505432

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

1

0

High-throughput

0.458

High

1108435

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1108437

ADCK1
AarF domain-containing protein kinase 1

1

0

High-throughput

0.458

High

1108447

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.458

High

327993

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

3

Small-scale

0.457

High

1108460

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

3

Small-scale

0.457

High

760753

CD68
Macrosialin

1

2

High-throughput

0.445

High

886051

CXCR3
C-X-C chemokine receptor type 3

1

5

High-throughput

0.445

High

1108425

MIC60
MICOS complex subunit MIC60

1

3

Small-scale

0.445

High

1108444

LPAR1
Lysophosphatidic acid receptor 1

1

6

High-throughput

0.445

High

1108476

MTCH2
Mitochondrial carrier homolog 2

1

6

High-throughput

0.445

High

588630

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

695388

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

768122

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

1108431

LMBRL
Protein LMBR1L

1

2

High-throughput

0.437

High

652188

GTR5
Solute carrier family 2, facilitated glucose transporter member 5

1

2

High-throughput

0.407

High

669318

ACKR3
Atypical chemokine receptor 3

1

7

High-throughput

0.407

High

332635

LYPD3
Ly6/PLAUR domain-containing protein 3

3

0

High-throughput

0.347

High

1108432

TM108
Transmembrane protein 108

2

0

High-throughput

0.328

High

1108453

SIG12
Sialic acid-binding Ig-like lectin 12

2

0

High-throughput

0.328

High

754020

CD80
T-lymphocyte activation antigen CD80

2

0

High-throughput

0.313

High

376955

GON1
Progonadoliberin-1

1

0

High-throughput

0.279

Low

378624

IL2RA
Interleukin-2 receptor subunit alpha

1

0

High-throughput

0.279

Low

914253

EFNA4
Ephrin-A4

1

0

High-throughput

0.279

Low

1108434

SO4C1
Solute carrier organic anion transporter family member 4C1

1

0

High-throughput

0.279

Low

1108436

PCAT2
Lysophosphatidylcholine acyltransferase 2

1

0

High-throughput

0.279

Low

1108469

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

407001

A1BG
Alpha-1B-glycoprotein

1

0

Small-scale

0.261

Low

385718

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.249

Low

964920

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.249

Low

1108462

SG196
Protein O-mannose kinase

1

0

High-throughput

0.249

Low

1108438

VSIG1
V-set and immunoglobulin domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025