HitPredict

Interactor 1: ITCH (Q8C863)
E3 ubiquitin-protein ligase Itchy (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase Itchy homolog)
Gene: ITCH

Interactor 2: NFIP1 (Q8R0W6)
NEDD4 family-interacting protein 1 (NEDD4 WW domain-binding protein 5)
Gene: Ndfip1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 17137798, 18819914
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005938 - cell cortex
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0016020 - membrane
GO:0030163 - protein catabolic process
GO:0035739 - CD4-positive, alpha-beta T cell proliferation
and 2 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 864
Mm

1 221
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Rn
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024