Interactor 1: AGO2 (Q8CJG0)
Protein argonaute-2 (Argonaute2) (mAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Piwi/argonaute family protein meIF2C2) (Protein slicer)
Gene: AGO2

Interactor 2: DICER (Q8R418)
Endoribonuclease Dicer (EC 3.1.26.3) (Double-strand-specific ribonuclease mDCR-1)
Gene: Dicer1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 22918229
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains ArgoL1~PAZ, ArgoL2~PAZ, PAZ~PAZ, PAZ~Ribonuclease_3, PAZ~Piwi
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0009791 - post-embryonic development
and 12 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 860
Mm

1 1916
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Ce
+ Ce
+ Hs
+ Hs
+ Ce
+ Hs
+ Ce
+ Ce
+ Hs
+ Ce
+ Dm
+ Dm
+ Dr

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024