Protein: BRM1L
Breast cancer metastasis-suppressor 1-like protein (BRMS1-homolog protein p40) (BRMS1-like protein p40)

Gene: BRM1L, BRMS1L
Organism: Homo sapiens
Interactions: 129
UniProt ID: Q5PSV4

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0030336 - negative regulation of cell migration
GO:0030512 - negative regulation of transforming growth factor beta receptor signaling pathway
GO:0042826 - histone deacetylase binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1109793

HDAC1
Histone deacetylase 1

9

10

Small-scale

0.975

High

282266

SAP30
Histone deacetylase complex subunit SAP30

4

3

Small-scale

0.895

High

1208643

ING2
Inhibitor of growth protein 2

3

13

Small-scale

0.861

High

1208634

SIN3A
Paired amphipathic helix protein Sin3a

3

9

Small-scale

0.827

High

1208625

HDAC2
Histone deacetylase 2

3

10

Small-scale

0.817

High

1208656

ING1
Inhibitor of growth protein 1

2

15

Small-scale

0.789

High

1208645

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

2

6

High-throughput

0.754

High

1158868

RBBP7
Histone-binding protein RBBP7

6

5

Small-scale

0.732

High

1066337

RBBP4
Histone-binding protein RBBP4

5

5

Small-scale

0.716

High

1208647

SHCAF
SIN3-HDAC complex-associated factor

4

2

Small-scale

0.691

High

1050740

MAD1
Max dimerization protein 1

3

9

High-throughput

0.667

High

1208614

LACC1
Purine nucleoside phosphorylase LACC1

3

1

High-throughput

0.667

High

1208611

ZN704
Zinc finger protein 704

3

2

High-throughput

0.662

High

1208659

AMOL2
Angiomotin-like protein 2

3

0

High-throughput

0.646

High

1208637

PHF23
PHD finger protein 23

2

1

High-throughput

0.628

High

274339

SIN3B
Paired amphipathic helix protein Sin3b

1

9

High-throughput

0.618

High

1208646

BRMS1
Breast cancer metastasis-suppressor 1

1

6

Small-scale

0.618

High

823843

PBX1
Pre-B-cell leukemia transcription factor 1

2

7

High-throughput

0.606

High

823891

PBX2
Pre-B-cell leukemia transcription factor 2

2

7

High-throughput

0.606

High

1208628

MCRS1
Microspherule protein 1

2

1

High-throughput

0.606

High

474039

NFIC
Nuclear factor 1 C-type

2

6

High-throughput

0.584

High

944676

KLF3
Krueppel-like factor 3

2

12

High-throughput

0.584

High

979783

H4
Histone H4

2

2

High-throughput

0.584

High

1133447

NFIX
Nuclear factor 1 X-type

2

6

High-throughput

0.584

High

1155441

EZH2
Histone-lysine N-methyltransferase EZH2

2

2

High-throughput

0.584

High

1208623

GATD1
GATA zinc finger domain-containing protein 1

2

2

High-throughput

0.584

High

1208638

MAD3
Max dimerization protein 3

2

9

High-throughput

0.574

High

1208619

CEP70
Centrosomal protein of 70 kDa

2

1

High-throughput

0.553

High

502011

H2AZ
Histone H2A.Z

1

2

High-throughput

0.536

High

711772

ARI4A
AT-rich interactive domain-containing protein 4A

1

4

High-throughput

0.536

High

959597

MAX
Protein max

1

7

High-throughput

0.536

High

997768

CSK21
Casein kinase II subunit alpha

1

4

High-throughput

0.536

High

1017432

FOXK1
Forkhead box protein K1

1

8

High-throughput

0.536

High

1029692

FOXK2
Forkhead box protein K2

1

8

High-throughput

0.536

High

1122994

FHL2
Four and a half LIM domains protein 2

1

2

High-throughput

0.536

High

1208613

TF2LX
Homeobox protein TGIF2LX

1

8

High-throughput

0.536

High

1208641

TGIF2
Homeobox protein TGIF2

1

7

High-throughput

0.536

High

1208649

LHX3
LIM/homeobox protein Lhx3

1

1

High-throughput

0.536

High

1208651

DAXX
Death domain-associated protein 6

1

1

High-throughput

0.536

High

1208654

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

1

High-throughput

0.523

High

279386

TULP3
Tubby-related protein 3

1

0

High-throughput

0.518

High

1208655

DDX41
Probable ATP-dependent RNA helicase DDX41

1

0

High-throughput

0.513

High

1208627

PF21B
PHD finger protein 21B

1

10

High-throughput

0.489

High

1208650

DKK2
Dickkopf-related protein 2

1

2

High-throughput

0.489

High

143035

NFIB
Nuclear factor 1 B-type

1

6

High-throughput

0.479

High

155315

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

1

High-throughput

0.479

High

168263

HAT1
Histone acetyltransferase type B catalytic subunit

1

1

High-throughput

0.479

High

210292

PHF1
PHD finger protein 1

1

3

High-throughput

0.479

High

225020

TLX3
T-cell leukemia homeobox protein 3

1

4

High-throughput

0.479

High

243656

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

9

High-throughput

0.479

High

248309

HBP1
HMG box-containing protein 1

1

10

High-throughput

0.479

High

285323

EED
Polycomb protein EED

1

1

High-throughput

0.479

High

316882

MTA2
Metastasis-associated protein MTA2

1

6

High-throughput

0.479

High

339772

KLF8
Krueppel-like factor 8

1

12

High-throughput

0.479

High

352159

MBD3
Methyl-CpG-binding domain protein 3

1

3

High-throughput

0.479

High

372228

MYC
Myc proto-oncogene protein

1

9

High-throughput

0.479

High

519518

MYBB
Myb-related protein B

1

1

High-throughput

0.479

High

662235

PAX7
Paired box protein Pax-7

1

5

High-throughput

0.479

High

685219

PAX6
Paired box protein Pax-6

1

3

High-throughput

0.479

High

703334

SMCA1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1

1

9

High-throughput

0.479

High

738990

ELF1
ETS-related transcription factor Elf-1

1

7

High-throughput

0.479

High

775853

HNF1B
Hepatocyte nuclear factor 1-beta

1

6

High-throughput

0.479

High

776080

SOX5
Transcription factor SOX-5

1

8

High-throughput

0.479

High

776203

SOX6
Transcription factor SOX-6

1

13

High-throughput

0.479

High

837052

ELK3
ETS domain-containing protein Elk-3

1

7

High-throughput

0.479

High

872405

SOX2
Transcription factor SOX-2

1

7

High-throughput

0.479

High

942104

SOX10
Transcription factor SOX-10

1

8

High-throughput

0.479

High

1040052

PAX2
Paired box protein Pax-2

1

3

High-throughput

0.479

High

1086778

BPTF
Nucleosome-remodeling factor subunit BPTF

1

5

High-throughput

0.479

High

1087781

NFIA
Nuclear factor 1 A-type

1

6

High-throughput

0.479

High

1088388

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

9

High-throughput

0.479

High

1094689

CAF1A
Chromatin assembly factor 1 subunit A

1

1

High-throughput

0.479

High

1095088

KLF10
Krueppel-like factor 10

1

9

High-throughput

0.479

High

1102564

MTA1
Metastasis-associated protein MTA1

1

6

High-throughput

0.479

High

1118654

KLF9
Krueppel-like factor 9

1

12

High-throughput

0.479

High

1132746

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

9

High-throughput

0.479

High

1137336

SUZ12
Polycomb protein SUZ12

1

1

High-throughput

0.479

High

1152696

ELF2
ETS-related transcription factor Elf-2

1

6

High-throughput

0.479

High

1195560

ARI4B
AT-rich interactive domain-containing protein 4B

1

4

High-throughput

0.479

High

1208612

P66A
Transcriptional repressor p66-alpha

1

3

High-throughput

0.479

High

1208620

SP7
Transcription factor Sp7

1

13

High-throughput

0.479

High

1208621

CHD5
Chromodomain-helicase-DNA-binding protein 5

1

9

High-throughput

0.479

High

1208622

ZN296
Zinc finger protein 296

1

4

High-throughput

0.479

High

1208624

P66B
Transcriptional repressor p66-beta

1

3

High-throughput

0.479

High

1208629

LIN37
Protein lin-37 homolog

1

1

High-throughput

0.479

High

1208631

PWP2A
PWWP domain-containing protein 2A

1

2

High-throughput

0.479

High

1208632

PHF12
PHD finger protein 12

1

10

High-throughput

0.479

High

1208633

CIC
Protein capicua homolog

1

7

High-throughput

0.479

High

1208635

FEV
Protein FEV

1

7

High-throughput

0.479

High

1208636

MTA3
Metastasis-associated protein MTA3

1

6

High-throughput

0.479

High

1208639

KLF16
Krueppel-like factor 16

1

11

High-throughput

0.479

High

1208642

SP130
Histone deacetylase complex subunit SAP130

1

7

High-throughput

0.479

High

1208644

BC11A
BCL11 transcription factor A

1

4

High-throughput

0.479

High

1208648

MBD2
Methyl-CpG-binding domain protein 2

1

3

High-throughput

0.479

High

1208653

KLF15
Krueppel-like factor 15

1

12

High-throughput

0.479

High

1208657

RCOR1
REST corepressor 1

1

6

High-throughput

0.479

High

1208658

BRPF3
Bromodomain and PHD finger-containing protein 3

1

1

High-throughput

0.479

High

1208660

MTF2
Metal-response element-binding transcription factor 2

1

3

High-throughput

0.479

High

1208661

KLF12
Krueppel-like factor 12

1

12

High-throughput

0.479

High

181522

TBXT
T-box transcription factor T

1

0

High-throughput

0.458

High

246649

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.458

High

419021

H2A1B
Histone H2A type 1-B/E

1

0

High-throughput

0.458

High

482153

RET1
Retinol-binding protein 1

1

0

Small-scale

0.458

High

581667

MYOD1
Myoblast determination protein 1

1

0

High-throughput

0.458

High

662440

GATA2
Endothelial transcription factor GATA-2

1

0

High-throughput

0.458

High

675532

TYY1
Transcriptional repressor protein YY1

1

0

High-throughput

0.458

High

833963

HNF4A
Hepatocyte nuclear factor 4-alpha

1

0

High-throughput

0.458

High

998405

H31
Histone H3.1

1

0

High-throughput

0.458

High

1052873

HME1
Homeobox protein engrailed-1

1

0

High-throughput

0.458

High

1094771

CAF1B
Chromatin assembly factor 1 subunit B

1

0

High-throughput

0.458

High

1208640

DPY30
Protein dpy-30 homolog

1

0

High-throughput

0.458

High

133861

FOXN3
Forkhead box protein N3

1

8

High-throughput

0.445

High

1135252

SHPRH
E3 ubiquitin-protein ligase SHPRH

1

11

High-throughput

0.437

High

1208610

LIN9
Protein lin-9 homolog

1

1

High-throughput

0.437

High

1208616

BAP18
BPTF-associated chromatin complex component 1

1

1

High-throughput

0.437

High

1208630

Z512B
Zinc finger protein 512B

1

1

High-throughput

0.437

High

1208652

HMGX4
HMG domain-containing protein 4

1

8

High-throughput

0.437

High

773749

ACTN2
Alpha-actinin-2

4

0

High-throughput

0.364

High

821114

TXLNA
Alpha-taxilin

2

0

High-throughput

0.316

High

1208617

TEX11
Testis-expressed protein 11

2

0

High-throughput

0.316

High

137235

EXOC5
Exocyst complex component 5

1

0

High-throughput

0.299

High

1053405

DEUP1
Deuterosome assembly protein 1

1

0

High-throughput

0.299

High

1208615

SULF2
Extracellular sulfatase Sulf-2

1

0

High-throughput

0.279

Low

374659

RASH
GTPase HRas

1

0

High-throughput

0.268

Low

650215

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.268

Low

1133875

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

0

High-throughput

0.268

Low

1197988

LIN52
Protein lin-52 homolog

1

0

High-throughput

0.249

Low

1208618

HJURP
Holliday junction recognition protein

1

0

High-throughput

0.249

Low

1208626

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025