HitPredict

Interactor 1: HSP72 (Q8INI8)
Major heat shock 70 kDa protein Ba (Heat shock protein 70Ba) (HSP70-87C1)
Gene: Hsp70Ba

Interactor 2: IKKB (Q9VEZ5)
Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappaB kinase subunit beta) (EC 2.7.11.10) (Cactus kinase IKK) (IKK-like protein) (Immune response deficient protein 5) (Lipopolysaccharide-activated kinase) (DLAK)
Gene: IKKbeta

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23749869
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 641 Dm			1 751
+	Dm
		1365056 HSP74_DROME (1-641): 0: 963: 99.84		IKKB_DROME (1-751): 0: 632: 100.00
+	Dm
		365410 HSP71_DROME (1-641): 0: 958: 98.29		IKKB_DROME (1-751): 0: 632: 100.00
+	Dm
		669799 HSP7A_DROME (1-641): 0: 953: 71.96		IKKB_DROME (1-751): 0: 632: 100.00
+	Dm
		332639 HSP68_DROME (1-641): 0: 930: 80.81		IKKB_DROME (1-751): 0: 632: 100.00
+	Dm
		505090 HSP7D_DROME (2-609): 0: 929: 76.19		IKKB_DROME (1-751): 0: 632: 100.00
+	Hs
		158411 HS71L_HUMAN (3-641): 0: 956: 74.38		IKKB_HUMAN (30-693): 6.04e-116: 369: 22.27
+	Hs
		158382 HSP7C_HUMAN (2-641): 0: 945: 74.18		IKKB_HUMAN (30-693): 6.04e-116: 369: 22.27
+	Hs
		504064 HSP7C_HUMAN (2-641): 0: 945: 74.18		IKKE_HUMAN (35-458): 2.84e-105: 339: 26.73
+	Hs
		1050214 Q53FC7_HUMAN (3-641): 0: 941: 70.94		IKKE_HUMAN (35-458): 2.84e-105: 339: 26.73
+	Hs
		503439 HSP7C_HUMAN (2-641): 0: 945: 74.18		KAPCG_HUMAN (30-355): 1.73e-106: 330: 22.87
+	Hs
		504911 HSP7C_HUMAN (2-641): 0: 945: 74.18		TBK1_HUMAN (35-461): 4.69e-83: 281: 24.44
+	Hs
		564016 HSP76_HUMAN (3-641): 0: 946: 71.41		AKT1_HUMAN (26-344): 1.08e-81: 270: 24.18
+	Hs
		503528 HSP7C_HUMAN (2-641): 0: 945: 74.18		AKT1_HUMAN (26-344): 1.08e-81: 270: 24.18
+	Hs
		564066 HSP76_HUMAN (3-641): 0: 946: 71.41		PAK1_HUMAN (41-288): 3.16e-21: 100: 30.59
+	Hs
		504007 HSP7C_HUMAN (2-641): 0: 945: 74.18		PAK1_HUMAN (41-288): 3.16e-21: 100: 30.59
+	Hs
		871551 HSP72_HUMAN (2-641): 0: 928: 73.56		PAK1_HUMAN (41-288): 3.16e-21: 100: 30.59