Interactor 1: CASP8 (Q8IRY7)
Caspase-8 (EC 3.4.22.61) (Death-related ced-3/NEDD2-like protein) [Cleaved into: Caspase-8 subunit p15; Caspase-8 subunit p10]
Gene: Dredd

Interactor 2: FADD (Q9V3B4)
Fas-associated death domain protein (Death domain-containing adapter protein BG4) (FAS-associating death domain-containing protein) (dFADD)
Gene: FADD

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 0.55 0.704

The method score is based on:

Property Details
Experiments 22450469, 10934188, 22549468, 21730059, 11606776, 14605208, unassigned4
Identification Methods affinity chromatography technology, two hybrid, experimental interaction detection
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002230 - positive regulation of defense response to virus by host
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006915 - apoptotic process
GO:0006955 - immune response
and 5 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024