HitPredict

Interactor 1: DCP2 (Q8IU60)
m7GpppN-mRNA hydrolase (EC 3.6.1.62) (Nucleoside diphosphate-linked moiety X motif 20) (Nudix motif 20) (mRNA-decapping enzyme 2) (hDpc)
Gene: DCP2

Interactor 2: PNRC2 (Q9NPJ4)
Proline-rich nuclear receptor coactivator 2
Gene: PNRC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 0.90 0.796

The method score is based on:

Property Details
Experiments 33961781, 23085078, 24510189
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DCP2~PNRC, NUDIX~PNRC
Common GO terms GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000932 - P-body
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024