HitPredict

Interactor 1: WFDC8 (Q8IUA0)
WAP four-disulfide core domain protein 8 (Putative protease inhibitor WAP8)
Gene: WFDC8

Interactor 2: APBB2 (Q92870)
Amyloid beta precursor protein binding family B member 2 (Amyloid-beta (A4) precursor protein-binding family B member 2) (Protein Fe65-like 1)
Gene: APBB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 241 Hs			1 758
+	Hs
		987529 APLP2_HUMAN (24-78): 9.28e-10: 60.2: 10.91		APBB2_HUMAN (1-758): 0: 1292: 100.00
+	Hs
		395373 A4_HUMAN (30-98): 3.96e-09: 58.3: 9.86		APBB2_HUMAN (1-758): 0: 1292: 100.00
+	Mm
		517702 A4_MOUSE (30-98): 2.33e-09: 59.1: 11.27		APBB2_MOUSE (1-758): 0: 1263: 93.95
+	Rn
		441680 A4_RAT (30-98): 1.08e-09: 60.2: 11.27		APBB1_RAT (20-758): 0: 956: 46.05
+	Mm
		517713 A4_MOUSE (30-98): 2.33e-09: 59.1: 11.27		APBB1_MOUSE (20-758): 0: 948: 46.25
+	Hs
		120816 CO6A3_HUMAN (24-76): 3.52e-10: 61.7: 7.55		APBB1_HUMAN (20-758): 0: 937: 45.46
+	Hs
		120897 APLP2_HUMAN (24-78): 9.28e-10: 60.2: 10.91		APBB1_HUMAN (20-758): 0: 937: 45.46
+	Hs
		120800 A4_HUMAN (30-98): 3.96e-09: 58.3: 9.86		APBB1_HUMAN (20-758): 0: 937: 45.46
+	Mm
		517679 A4_MOUSE (30-98): 2.33e-09: 59.1: 11.27		APBB3_MOUSE (277-757): 0: 686: 39.22
+	Rn
		193495 A4_RAT (30-98): 1.08e-09: 60.2: 11.27		APBB3_RAT (277-758): 0: 684: 39.57
+	Hs
		319411 APLP2_HUMAN (24-78): 9.28e-10: 60.2: 10.91		APBB3_HUMAN (277-758): 0: 680: 39.92
+	Hs
		319403 A4_HUMAN (30-98): 3.96e-09: 58.3: 9.86		APBB3_HUMAN (277-758): 0: 680: 39.92