Protein: LCE5A
Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A)

Gene: LCE5A
Organism: Homo sapiens
Interactions: 92
UniProt ID: Q5TCM9

Gene Ontology (top 5):
GO:0031424 - keratinization
GO:0042802 - identical protein binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1213899

LCE1C
Late cornified envelope protein 1C

2

2

High-throughput

0.606

High

1213983

LCE1E
Late cornified envelope protein 1E

2

1

High-throughput

0.606

High

1214301

LCE1B
Late cornified envelope protein 1B

2

1

High-throughput

0.606

High

1215167

LCE2C
Late cornified envelope protein 2C

2

2

High-throughput

0.606

High

950792

KR109
Keratin-associated protein 10-9

3

20

High-throughput

0.603

High

1215928

LCE5A
Late cornified envelope protein 5A

2

0

High-throughput

0.589

High

159066

LCE2B
Late cornified envelope protein 2B

2

0

High-throughput

0.580

High

1186631

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.580

High

1214021

LCE1F
Late cornified envelope protein 1F

2

0

High-throughput

0.580

High

1214258

LCE1A
Late cornified envelope protein 1A

2

0

High-throughput

0.580

High

1215097

LCE4A
Late cornified envelope protein 4A

2

0

High-throughput

0.580

High

1215932

KRA54
Keratin-associated protein 5-4

2

13

High-throughput

0.561

High

1215933

KRA53
Keratin-associated protein 5-3

2

16

High-throughput

0.561

High

1215949

KR412
Keratin-associated protein 4-12

2

20

High-throughput

0.561

High

74127

VWC2L
von Willebrand factor C domain-containing protein 2-like

2

2

High-throughput

0.553

High

221368

SPY1
Protein sprouty homolog 1

2

1

High-throughput

0.553

High

303151

RGS20
Regulator of G-protein signaling 20

2

1

High-throughput

0.553

High

685878

KRA59
Keratin-associated protein 5-9

2

20

High-throughput

0.553

High

949565

KR123
Keratin-associated protein 12-3

2

2

High-throughput

0.553

High

950285

KR107
Keratin-associated protein 10-7

2

17

High-throughput

0.553

High

950524

KR108
Keratin-associated protein 10-8

2

19

High-throughput

0.553

High

1059661

KRA11
Keratin-associated protein 1-1

2

20

High-throughput

0.553

High

1215930

KR511
Keratin-associated protein 5-11

2

18

High-throughput

0.553

High

1215939

SPRE2
Sprouty-related, EVH1 domain-containing protein 2

2

1

High-throughput

0.553

High

1215940

KRA13
Keratin-associated protein 1-3

2

19

High-throughput

0.553

High

1215951

KRA93
Keratin-associated protein 9-3

2

20

High-throughput

0.553

High

1215952

KRA92
Keratin-associated protein 9-2

2

20

High-throughput

0.553

High

1215953

KR411
Keratin-associated protein 4-11

2

20

High-throughput

0.553

High

1215954

KRA41
Keratin-associated protein 4-1

2

20

High-throughput

0.553

High

1215955

KRA45
Keratin-associated protein 4-5

2

20

High-throughput

0.553

High

1215956

KRA44
Keratin-associated protein 4-4

2

20

High-throughput

0.553

High

1215957

KRA42
Keratin-associated protein 4-2

2

20

High-throughput

0.553

High

1215959

KRA15
Keratin-associated protein 1-5

2

20

High-throughput

0.553

High

1215960

CHRD
Chordin

2

2

High-throughput

0.553

High

1215961

PLS4
Phospholipid scramblase 4

2

2

High-throughput

0.553

High

1215962

PLS3
Phospholipid scramblase 3

2

2

High-throughput

0.553

High

1215963

PLS2
Phospholipid scramblase 2

2

2

High-throughput

0.553

High

1215965

RGS17
Regulator of G-protein signaling 17

2

1

High-throughput

0.553

High

1186745

KRA63
Keratin-associated protein 6-3

1

0

High-throughput

0.493

High

1215074

LCE3B
Late cornified envelope protein 3B

1

1

High-throughput

0.481

High

1215136

LCE2A
Late cornified envelope protein 2A

1

1

High-throughput

0.481

High

1215210

LCE2D
Late cornified envelope protein 2D

1

2

High-throughput

0.481

High

517031

NT2NC
Notch homolog 2 N-terminal-like protein C

1

1

High-throughput

0.470

High

950077

KR105
Keratin-associated protein 10-5

1

19

High-throughput

0.470

High

1065873

Q08AG9
Steroid 21-hydroxylase

1

1

High-throughput

0.470

High

1215936

Q7KZS0
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.470

High

1215947

Q96EJ4
PLAC8 protein

1

1

High-throughput

0.470

High

1212897

LCE3C
Late cornified envelope protein 3C

1

0

High-throughput

0.460

High

1213941

LCE1D
Late cornified envelope protein 1D

1

0

High-throughput

0.460

High

291036

KRA58
Keratin-associated protein 5-8

1

17

High-throughput

0.439

High

475208

CP21A
Steroid 21-hydroxylase

1

1

High-throughput

0.439

High

505339

KRA23
Keratin-associated protein 2-3

1

20

High-throughput

0.439

High

948284

KR121
Keratin-associated protein 12-1

1

2

High-throughput

0.439

High

948340

KR122
Keratin-associated protein 12-2

1

20

High-throughput

0.439

High

949718

KR101
Keratin-associated protein 10-1

1

20

High-throughput

0.439

High

950170

KR106
Keratin-associated protein 10-6

1

17

High-throughput

0.439

High

993614

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.439

High

1180101

VWC2
Brorin

1

2

High-throughput

0.439

High

1215937

NT2NA
Notch homolog 2 N-terminal-like protein A

1

1

High-throughput

0.439

High

1215950

KRA98
Keratin-associated protein 9-8

1

20

High-throughput

0.439

High

1215964

PLAC8
Placenta-specific gene 8 protein

1

1

High-throughput

0.439

High

70272

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

209895

ADA12
Disintegrin and metalloproteinase domain-containing protein 12

2

0

High-throughput

0.316

High

426101

PPB1
Alkaline phosphatase, placental type

2

0

High-throughput

0.316

High

654514

FBLN1
Fibulin-1

2

0

High-throughput

0.316

High

885286

HXA1
Homeobox protein Hox-A1

2

0

High-throughput

0.316

High

892213

MCSP
Sperm mitochondrial-associated cysteine-rich protein

2

0

High-throughput

0.316

High

949661

KR124
Keratin-associated protein 12-4

2

0

High-throughput

0.316

High

965556

NTF2
Nuclear transport factor 2

2

0

High-throughput

0.316

High

1004685

RNF4
E3 ubiquitin-protein ligase RNF4

2

0

High-throughput

0.316

High

1039760

CREB5
Cyclic AMP-responsive element-binding protein 5

2

0

High-throughput

0.316

High

1086967

PO4F2
POU domain, class 4, transcription factor 2

2

0

High-throughput

0.316

High

1186546

KR212
Keratin-associated protein 21-2

2

0

High-throughput

0.316

High

1215931

KRA56
Keratin-associated protein 5-6

2

0

High-throughput

0.316

High

1215935

KRA52
Keratin-associated protein 5-2

2

0

High-throughput

0.316

High

1215941

TRI42
Tripartite motif-containing protein 42

2

0

High-throughput

0.316

High

1215943

ZN655
Zinc finger protein 655

2

0

High-throughput

0.316

High

1215945

S39A7
Zinc transporter SLC39A7

2

0

High-throughput

0.316

High

1215946

NECT2
Nectin-2

2

0

High-throughput

0.316

High

1215948

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.316

High

1215958

KRA31
Keratin-associated protein 3-1

2

0

High-throughput

0.316

High

1215966

CHIC2
Cysteine-rich hydrophobic domain-containing protein 2

2

0

High-throughput

0.316

High

546

NBPFJ
NBPF family member NBPF19

1

0

High-throughput

0.251

Low

192096

PA2GX
Group 10 secretory phospholipase A2

1

0

High-throughput

0.251

Low

376856

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.251

Low

705395

GRN
Progranulin

1

0

High-throughput

0.251

Low

1215929

VASN
Vasorin

1

0

High-throughput

0.251

Low

1215934

ATL4
ADAMTS-like protein 4

1

0

High-throughput

0.251

Low

1215938

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.251

Low

1215942

MACOI
Macoilin

1

0

High-throughput

0.251

Low

1215944

CTSR1
Cation channel sperm-associated protein 1

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025