HitPredict

Interactor 1: RB6I2 (Q8IUD2)
ELKS/Rab6-interacting/CAST family member 1 (ERC-1) (Rab6-interacting protein 2)
Gene: ERC1

Interactor 2: RAB6B (Q9NRW1)
Ras-related protein Rab-6B (EC 3.6.5.2)
Gene: RAB6B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	11929610
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	RBD-FIP~Ras
Common GO terms	GO:0000139 - Golgi membrane GO:0042147 - retrograde transport, endosome to Golgi
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1116 Hs			1 208
+	Hs
		592678 RB6I2_HUMAN (1-1116): 2.23e-82: 293: 100.00		RAB6A_HUMAN (1-208): 1.37e-84: 250: 90.87
+	Dm
		185621 MYSN_DROME (523-1115): 2.29e-26: 119: 12.29		RAB6_DROME (1-208): 7.05e-90: 264: 84.21
+	Hs
		592265 EEA1_HUMAN (557-1116): 4.52e-19: 95.6: 12.23		RAB5A_HUMAN (3-207): 4.67e-89: 262: 40.78
+	Hs
		844532 EEA1_HUMAN (557-1116): 4.52e-19: 95.6: 12.23		RAB5C_HUMAN (3-207): 3.56e-89: 262: 40.98
+	Hs
		148389 CTRO_HUMAN (156-792): 2.47e-18: 93.5: 12.63		RAB5A_HUMAN (3-207): 4.67e-89: 262: 40.78
+	Hs
		148636 CTRO_HUMAN (156-792): 2.47e-18: 93.5: 12.63		RAB1A_HUMAN (1-207): 7.26e-89: 261: 34.30
+	Hs
		149274 CTRO_HUMAN (156-792): 2.47e-18: 93.5: 12.63		RAB1B_HUMAN (7-206): 1.58e-87: 258: 35.50
+	Sc
		350851 USO1_YEAST (237-915): 3.06e-11: 70.1: 20.06		YPT1_YEAST (7-207): 7.56e-89: 261: 37.38
+	Ce
		219445 O44490_CAEEL (161-834): 3.6e-09: 63.2: 20.15		Q9UAQ6_CAEEL (1-206): 3.34e-89: 262: 35.75
+	Ce
		218533 O44490_CAEEL (161-834): 3.6e-09: 63.2: 20.15		RAB6A_CAEEL (7-208): 7.02e-89: 261: 74.88
+	Hs
		895354 EEA1_HUMAN (557-1116): 4.52e-19: 95.6: 12.23		RAB5B_HUMAN (13-178): 5.66e-49: 160: 45.78
+	Mm
		1206850 EEA1_MOUSE (584-1116): 6.1e-20: 98.6: 11.19		RAB31_MOUSE (11-191): 1.76e-44: 148: 36.46
+	Hs
		1044476 EEA1_HUMAN (557-1116): 4.52e-19: 95.6: 12.23		RAB31_HUMAN (11-196): 5.59e-45: 149: 36.56
+	Ce
		218716 O44490_CAEEL (161-834): 3.6e-09: 63.2: 20.15		P91857_CAEEL (8-206): 2.71e-50: 163: 40.30
+	Hs
		895213 MY18A_HUMAN (439-976): 3.58e-09: 63.5: 18.73		RAB2A_HUMAN (14-191): 5.16e-45: 150: 39.89
+	Ce
		136537 O44490_CAEEL (161-834): 3.6e-09: 63.2: 20.15		O01577_CAEEL (14-202): 2.6e-44: 148: 37.95