Interactor 1: ZDH17 (Q8IUH5)
Palmitoyltransferase ZDHHC17 (EC 2.3.1.225) (Acyltransferase ZDHHC17) (EC 2.3.1.-) (DHHC domain-containing cysteine-rich protein 17) (DHHC17) (Huntingtin yeast partner H) (Huntingtin-interacting protein 14) (HIP-14) (Huntingtin-interacting protein 3) (HIP-3) (Huntingtin-interacting protein H) (Putative MAPK-activating protein PM11) (Putative NF-kappa-B-activating protein 205) (Zinc finger DHHC domain-containing protein 17)
Gene: ZDHHC17

Interactor 2: OPTN (Q96CV9)
Optineurin (E3-14.7K-interacting protein) (FIP-2) (Huntingtin yeast partner L) (Huntingtin-interacting protein 7) (HIP-7) (Huntingtin-interacting protein L) (NEMO-related protein) (Optic neuropathy-inducing protein) (Transcription factor IIIA-interacting protein) (TFIIIA-IntP)
Gene: OPTN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.764

The method score is based on:

Property Details
Experiments 24705354
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid array, luminescence based mammalian interactome mapping
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~CC2-LZ
Common GO terms GO:0000139 - Golgi membrane
GO:0005794 - Golgi apparatus
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 632
Hs

1 577
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Last updated: 15 Jul 2024