HitPredict

Interactor 1: Q5U5U6 (Q5U5U6)
Epididymis secretory protein Li 50 (Ubiquitin B)
Gene: UBB

Interactor 2: UBQL1 (Q9UMX0)
Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1)
Gene: UBQLN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.80	0.594

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UBA~ubiquitin, ubiquitin~ubiquitin
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 229 Hs			1 589
+	Hs
		507423 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		UBQL1_HUMAN (1-589): 1.24e-174: 509: 100.00
+	Hs
		1385479 Q96C32_HUMAN (1-228): 2.15e-96: 285: 100.00		UBQL1_HUMAN (1-589): 1.24e-174: 509: 100.00
+	Hs
		508829 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		UBQL1_HUMAN (1-589): 1.24e-174: 509: 100.00
+	Hs
		507405 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		UBQL2_HUMAN (1-589): 9.56e-145: 433: 71.29
+	Hs
		508786 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		UBQL2_HUMAN (1-589): 9.56e-145: 433: 71.29
+	Xl
		1274151 Q7SY79_XENLA (1-228): 1.28e-92: 285: 100.00		Q9PVN8_XENLA (16-589): 3.65e-137: 413: 57.71
+	Hs
		508691 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		UBQL4_HUMAN (28-589): 1.36e-135: 409: 57.64
+	Mm
		509314 UBC_MOUSE (1-181): 8.42e-63: 209: 96.13		UBQL2_MOUSE (1-589): 8.37e-141: 424: 65.47
+	Hs
		508332 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		DDI1_HUMAN (47-318): 6.42e-53: 187: 15.60
+	Dm
		1488222 Q9W418_DROME (1-228): 1.41e-93: 285: 100.00		Q9VXF9_DROME (37-317): 4.1e-51: 184: 17.93
+	Hs
		508111 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		DDI2_HUMAN (47-318): 2.04e-49: 178: 13.52
+	Hs
		507149 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		RL40_HUMAN (37-126): 1.89e-34: 128: 30.77
+	Hs
		507798 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		RL40_HUMAN (37-126): 1.89e-34: 128: 30.77
+	Dm
		612445 Q9W418_DROME (1-228): 1.41e-93: 285: 100.00		RL40_DROME (37-126): 7.86e-34: 126: 29.67
+	Sc
		509460 UBI4P_YEAST (1-228): 3.4e-91: 274: 96.05		RAD23_YEAST (45-419): 1.18e-31: 128: 17.73
+	Sc
		509631 UBI4P_YEAST (1-228): 3.4e-91: 274: 96.05		DSK2_YEAST (36-243): 8.2e-32: 128: 30.73
+	Mm
		59252 UBC_MOUSE (1-181): 8.42e-63: 209: 96.13		DDI2_MOUSE (47-318): 5.97e-50: 179: 14.39
+	Hs
		507148 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		RS27A_HUMAN (37-123): 1.11e-12: 68: 30.68
+	Hs
		507797 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		RS27A_HUMAN (37-123): 1.11e-12: 68: 30.68
+	At
		1167723 UBQ3_ARATH (1-228): 1.09e-94: 281: 96.05		Q8L745_ARATH (23-139): 2.77e-12: 71.8: 23.73