Protein: INP5K
Inositol polyphosphate 5-phosphatase K (EC 3.1.3.56) (Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase) (EC 3.1.3.86) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (EC 3.1.3.36) (Skeletal muscle and kidney-enriched inositol phosphatase)

Gene: INP5K, INPP5K
Organism: Homo sapiens
Interactions: 68
UniProt ID: Q9BT40

Gene Ontology (top 5):
GO:0001701 - in utero embryonic development
GO:0001726 - ruffle
GO:0001933 - negative regulation of protein phosphorylation
GO:0004439 - phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO:0004445 - inositol-polyphosphate 5-phosphatase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1062971

MD2BP
MAD2L1-binding protein

6

0

High-throughput

0.707

High

1071361

K1H1
Keratin, type I cuticular Ha1

4

12

High-throughput

0.704

High

1065306

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

4

0

High-throughput

0.671

High

1281109

FATE1
Fetal and adult testis-expressed transcript protein

4

0

High-throughput

0.668

High

604191

PUR2
Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase

3

0

High-throughput

0.646

High

1044879

AAMP
Angio-associated migratory cell protein

3

0

High-throughput

0.638

High

1311810

NECT3
Nectin-3

3

0

High-throughput

0.638

High

265425

KTNA1
Katanin p60 ATPase-containing subunit A1

2

2

High-throughput

0.628

High

475170

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

3

High-throughput

0.628

High

1295893

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

2

2

High-throughput

0.628

High

1311815

TR10D
Tumor necrosis factor receptor superfamily member 10D

2

2

High-throughput

0.606

High

1311818

GOT1B
Vesicle transport protein GOT1B

2

1

High-throughput

0.606

High

132204

PESC
Pescadillo homolog

2

0

High-throughput

0.602

High

1311812

ABHDA
Palmitoyl-protein thioesterase ABHD10, mitochondrial

2

0

High-throughput

0.602

High

316397

SFT2B
Vesicle transport protein SFT2B

2

0

High-throughput

0.580

High

1238381

FADS6
Fatty acid desaturase 6

2

0

High-throughput

0.580

High

610181

RFX1
MHC class II regulatory factor RFX1

2

1

High-throughput

0.574

High

1311813

ARL8B
ADP-ribosylation factor-like protein 8B

1

7

Small-scale

0.573

High

500063

CH60
60 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.536

High

817537

RFX3
Transcription factor RFX3

1

1

High-throughput

0.536

High

1050491

DOCK1
Dedicator of cytokinesis protein 1

1

2

High-throughput

0.536

High

1055078

KT33B
Keratin, type I cuticular Ha3-II

1

12

High-throughput

0.536

High

1056962

MDC1
Mediator of DNA damage checkpoint protein 1

1

1

High-throughput

0.536

High

1311817

SNX6
Sorting nexin-6

1

4

High-throughput

0.536

High

388699

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.518

High

618298

BDNF
Brain-derived neurotrophic factor

1

0

High-throughput

0.518

High

1135545

CPTP
Ceramide-1-phosphate transfer protein

1

0

High-throughput

0.518

High

1271751

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.518

High

1284334

Q96AL5
PBX3 protein

1

1

High-throughput

0.515

High

532203

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.513

High

1160888

FXL19
F-box/LRR-repeat protein 19

1

0

High-throughput

0.513

High

1218950

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1293241

NTAQ1
Protein N-terminal glutamine amidohydrolase

1

0

High-throughput

0.513

High

1311807

GAN
Gigaxonin

1

0

High-throughput

0.513

High

589239

ANXA7
Annexin A7

1

2

High-throughput

0.508

High

1252439

LNX1
E3 ubiquitin-protein ligase LNX

1

3

Small-scale

0.506

High

310086

TNKS1
Poly [ADP-ribose] polymerase tankyrase-1

1

1

High-throughput

0.501

High

1311820

RIPK3
Receptor-interacting serine/threonine-protein kinase 3

1

0

High-throughput

0.493

High

1271949

KLK6
Kallikrein-6

1

0

High-throughput

0.493

High

1311808

MTG2
Mitochondrial ribosome-associated GTPase 2

1

5

High-throughput

0.489

High

246033

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.486

High

378765

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.486

High

674243

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.486

High

758325

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.486

High

1084886

SMN
Survival motor neuron protein

1

0

High-throughput

0.486

High

773206

PBX3
Pre-B-cell leukemia transcription factor 3

1

1

High-throughput

0.481

High

1311821

NCOR2
Nuclear receptor corepressor 2

1

3

Small-scale

0.481

High

1311819

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

228525

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

885303

EPIPL
Epiplakin

1

2

High-throughput

0.479

High

1066611

KIF14
Kinesin-like protein KIF14

1

3

High-throughput

0.479

High

1311811

ANLN
Anillin

1

1

High-throughput

0.479

High

506264

PYGM
Glycogen phosphorylase, muscle form

1

0

High-throughput

0.458

High

649704

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.458

High

909041

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

946601

DCD
Dermcidin

1

0

High-throughput

0.458

High

1311809

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1311814

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.458

High

1311816

BRPF3
Bromodomain and PHD finger-containing protein 3

1

0

High-throughput

0.458

High

882532

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

12

High-throughput

0.445

High

529654

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

1203380

PRSR2
Proline and serine-rich protein 2

2

0

High-throughput

0.328

High

579595

ATP5J
ATP synthase-coupling factor 6, mitochondrial

2

0

High-throughput

0.316

High

1242424

CA131
Uncharacterized protein C1orf131

1

0

High-throughput

0.279

Low

363648

TTHY
Transthyretin

1

0

High-throughput

0.265

Low

1160440

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

0

High-throughput

0.249

Low

1220975

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.249

Low

1303068

GPHA2
Glycoprotein hormone alpha-2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024