HitPredict

Interactor 1: UBB (P0CG47)
Polyubiquitin-B [Cleaved into: Ubiquitin]
Gene: UBB

Interactor 2: UBQL1 (Q9UMX0)
Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1)
Gene: UBQLN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	25416956
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UBA~ubiquitin, ubiquitin~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0031398 - positive regulation of protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 229 Hs			1 589
+	Hs
		1217034 Q5U5U6_HUMAN (1-229): 2.65e-99: 289: 100.00		UBQL1_HUMAN (1-589): 1.24e-174: 509: 100.00
+	Hs
		1385479 Q96C32_HUMAN (1-228): 2.15e-96: 285: 100.00		UBQL1_HUMAN (1-589): 1.24e-174: 509: 100.00
+	Hs
		508829 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		UBQL1_HUMAN (1-589): 1.24e-174: 509: 100.00
+	Hs
		507405 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		UBQL2_HUMAN (1-589): 9.56e-145: 433: 71.29
+	Hs
		508786 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		UBQL2_HUMAN (1-589): 9.56e-145: 433: 71.29
+	Xl
		1274151 Q7SY79_XENLA (1-228): 1.28e-92: 285: 100.00		Q9PVN8_XENLA (16-589): 3.65e-137: 413: 57.71
+	Hs
		508691 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		UBQL4_HUMAN (28-589): 1.36e-135: 409: 57.64
+	Mm
		509314 UBC_MOUSE (1-181): 8.42e-63: 209: 96.13		UBQL2_MOUSE (1-589): 8.37e-141: 424: 65.47
+	Hs
		508332 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		DDI1_HUMAN (47-318): 6.42e-53: 187: 15.60
+	Dm
		1488222 Q9W418_DROME (1-228): 1.41e-93: 285: 100.00		Q9VXF9_DROME (37-317): 4.1e-51: 184: 17.93
+	Hs
		508111 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		DDI2_HUMAN (47-318): 2.04e-49: 178: 13.52
+	Hs
		507149 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		RL40_HUMAN (37-126): 1.89e-34: 128: 30.77
+	Hs
		507798 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		RL40_HUMAN (37-126): 1.89e-34: 128: 30.77
+	Dm
		612445 Q9W418_DROME (1-228): 1.41e-93: 285: 100.00		RL40_DROME (37-126): 7.86e-34: 126: 29.67
+	Sc
		509460 UBI4P_YEAST (1-228): 3.4e-91: 274: 96.05		RAD23_YEAST (45-419): 1.18e-31: 128: 17.73
+	Sc
		509631 UBI4P_YEAST (1-228): 3.4e-91: 274: 96.05		DSK2_YEAST (36-243): 8.2e-32: 128: 30.73
+	Mm
		59252 UBC_MOUSE (1-181): 8.42e-63: 209: 96.13		DDI2_MOUSE (47-318): 5.97e-50: 179: 14.39
+	Hs
		507148 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		RS27A_HUMAN (37-123): 1.11e-12: 68: 30.68
+	Hs
		507797 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		RS27A_HUMAN (37-123): 1.11e-12: 68: 30.68
+	At
		1167723 UBQ3_ARATH (1-228): 1.09e-94: 281: 96.05		Q8L745_ARATH (23-139): 2.77e-12: 71.8: 23.73