HitPredict

Interactor 1: LMTK2 (Q8IWU2)
Serine/threonine-protein kinase LMTK2 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase 2) (Brain-enriched kinase) (hBREK) (CDK5/p35-regulated kinase) (CPRK) (Kinase/phosphatase/inhibitor 2) (Lemur tyrosine kinase 2) (Serine/threonine-protein kinase KPI-2)
Gene: LMTK2

Interactor 2: STYX (Q8WUJ0)
Serine/threonine/tyrosine-interacting protein (Inactive tyrosine-protein phosphatase STYX) (Phosphoserine/threonine/tyrosine interaction protein)
Gene: STYX

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.50	0.494

Property	Details
Experiments	28065597
Identification Methods	two hybrid, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1503 Hs			1 223
+	Hs
		304988 LMTK2_HUMAN (1-1503): 0: 1232: 100.00		DUS14_HUMAN (7-185): 4.2e-63: 196: 31.84
+	Hs
		1088020 LMTK2_HUMAN (1-1503): 0: 1232: 100.00		DUS6_HUMAN (16-188): 4.93e-57: 186: 29.89
+	Hs
		1148510 LMTK2_HUMAN (1-1503): 0: 1232: 100.00		DUS29_HUMAN (22-174): 2.63e-56: 180: 30.77
+	Hs
		1219431 LMTK2_HUMAN (1-1503): 0: 1232: 100.00		DUS19_HUMAN (32-187): 5.31e-55: 176: 33.97
+	Hs
		1168392 LMTK1_HUMAN (14-1500): 0: 702: 29.02		STYX_HUMAN (1-223): 9.96e-91: 267: 100.00
+	Hs
		659292 LMTK1_HUMAN (14-1500): 0: 702: 29.02		DUS1_HUMAN (4-199): 1.03e-64: 206: 29.59
+	Hs
		1086145 LMTK1_HUMAN (14-1500): 0: 702: 29.02		DUS5_HUMAN (2-203): 4.01e-62: 200: 29.27
+	Hs
		1168409 LMTK1_HUMAN (14-1500): 0: 702: 29.02		DUS9_HUMAN (3-191): 6.24e-61: 197: 28.13
+	Hs
		304979 LMTK1_HUMAN (14-1500): 0: 702: 29.02		DUS14_HUMAN (7-185): 4.2e-63: 196: 31.84
+	Hs
		1088015 LMTK1_HUMAN (14-1500): 0: 702: 29.02		DUS6_HUMAN (16-188): 4.93e-57: 186: 29.89
+	Hs
		1148509 LMTK1_HUMAN (14-1500): 0: 702: 29.02		DUS29_HUMAN (22-174): 2.63e-56: 180: 30.77
+	Hs
		1070989 ERBB4_HUMAN (17-748): 3.15e-132: 444: 18.30		STYX_HUMAN (1-223): 9.96e-91: 267: 100.00
+	Hs
		304961 ERBB4_HUMAN (17-748): 3.15e-132: 444: 18.30		DUS14_HUMAN (7-185): 4.2e-63: 196: 31.84
+	Hs
		1071007 ERBB4_HUMAN (17-748): 3.15e-132: 444: 18.30		DUS16_HUMAN (7-186): 2.52e-56: 191: 27.22
+	Hs
		1070972 ERBB4_HUMAN (17-748): 3.15e-132: 444: 18.30		DUS6_HUMAN (16-188): 4.93e-57: 186: 29.89
+	Hs
		1070986 ERBB4_HUMAN (17-748): 3.15e-132: 444: 18.30		DUS18_HUMAN (10-185): 5.17e-58: 183: 26.71
+	Hs
		1070988 ERBB4_HUMAN (17-748): 3.15e-132: 444: 18.30		DUS19_HUMAN (32-187): 5.31e-55: 176: 33.97
+	Hs
		1071012 ERBB4_HUMAN (17-748): 3.15e-132: 444: 18.30		DUS21_HUMAN (19-185): 6.37e-55: 175: 26.95
+	Hs
		304916 FGFR2_HUMAN (33-454): 4.84e-123: 406: 20.31		DUS14_HUMAN (7-185): 4.2e-63: 196: 31.84
+	Hs
		434278 RET_HUMAN (5-489): 2.25e-120: 407: 18.93		DUS26_HUMAN (27-176): 1.44e-56: 180: 30.46