HitPredict

Interactor 1: NPAS3 (Q8IXF0)
Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Basic-helix-loop-helix-PAS protein MOP6) (Class E basic helix-loop-helix protein 12) (bHLHe12) (Member of PAS protein 6) (PAS domain-containing protein 6)
Gene: NPAS3

Interactor 2: ARNT2 (Q9HBZ2)
Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2) (Class E basic helix-loop-helix protein 1) (bHLHe1)
Gene: ARNT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.817

The method score is based on:

Property Details
Experiments 33961781, 24722188
Identification Methods affinity chromatography technology, two hybrid, two hybrid array, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains HLH~PAS, PAS~PAS, PAS~PAS_11, PAS~PAS_3, PAS_11~PAS_3
Common GO terms GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0045893 - positive regulation of DNA-templated transcription
and 1 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

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Last updated: 15 Jul 2024