HitPredict

Interactor 1: FBXW9 (Q5XUX1)
F-box/WD repeat-containing protein 9 (F-box and WD-40 domain-containing protein 9)
Gene: FBXW9

Interactor 2: HERC5 (Q9UII4)
E3 ISG15--protein ligase HERC5 (EC 2.3.2.-) (Cyclin-E-binding protein 1) (HECT domain and RCC1-like domain-containing protein 5)
Gene: HERC5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35671810
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 458 Hs			1 1024
+	Hs
		1380237 FBXW7_HUMAN (52-410): 8.14e-78: 257: 16.62		HERC5_HUMAN (16-1024): 0: 1018: 100.00
+	Hs
		1460423 FBW1A_HUMAN (59-222): 7.01e-15: 78.8: 12.64		HERC5_HUMAN (16-1024): 0: 1018: 100.00
+	Hs
		964876 WDR5_HUMAN (381-458): 9.45e-15: 76.8: 23.17		UBE3A_HUMAN (363-1024): 0: 567: 23.66
+	Hs
		131888 WDR5_HUMAN (381-458): 9.45e-15: 76.8: 23.17		WWP2_HUMAN (547-1024): 0: 550: 19.68
+	Hs
		861847 FBW1A_HUMAN (59-222): 7.01e-15: 78.8: 12.64		NEDD4_HUMAN (576-1023): 5.67e-169: 532: 21.99
+	Hs
		1437708 FBW1A_HUMAN (59-222): 7.01e-15: 78.8: 12.64		SMUF2_HUMAN (581-1024): 9.35e-169: 514: 24.29
+	Hs
		1439013 FBW1A_HUMAN (59-222): 7.01e-15: 78.8: 12.64		SMUF1_HUMAN (577-1024): 7.17e-168: 512: 23.54
+	Hs
		1138989 FBW1A_HUMAN (59-222): 7.01e-15: 78.8: 12.64		HERC3_HUMAN (317-460): 9.5e-15: 81.2: 10.20
+	Hs
		1138986 FBW1B_HUMAN (59-222): 1.72e-14: 77.6: 13.22		HERC3_HUMAN (317-460): 9.5e-15: 81.2: 10.20