HitPredict

Interactor 1: SMC5 (Q8IY18)
Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5) (hSMC5)
Gene: SMC5

Interactor 2: TR150 (Q9Y2W1)
Thyroid hormone receptor-associated protein 3 (BCLAF1 and THRAP3 family member 2) (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150)
Gene: THRAP3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36373674
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1101 Hs			1 955
+	Hs
		1357885 SMC3_HUMAN (51-1061): 6.65e-82: 293: 13.91		TR150_HUMAN (1-955): 9.81e-127: 408: 100.00
+	Hs
		1221784 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		BCLF1_HUMAN (38-949): 3.55e-78: 276: 33.19
+	Hs
		1191687 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		RBBP6_HUMAN (20-841): 1.66e-72: 264: 13.81
+	Hs
		1221605 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		ELYS_HUMAN (244-849): 8.04e-60: 226: 8.74
+	Hs
		1221841 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		1056884 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		MDC1_HUMAN (2-649): 1.14e-11: 71.2: 8.49
+	Hs
		1154049 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		NIPBL_HUMAN (138-674): 7.25e-11: 68.9: 13.20
+	Mm
		1154102 SMC3_MOUSE (51-1061): 1.42e-81: 292: 13.91		NIPBL_MOUSE (112-674): 2.74e-11: 70: 14.71
+	Hs
		1154087 SMC3_HUMAN (51-1061): 6.65e-82: 293: 13.91		NIPBL_HUMAN (138-674): 7.25e-11: 68.9: 13.20
+	Hs
		1056947 SMC6_HUMAN (9-1069): 7.85e-63: 235: 15.55		MDC1_HUMAN (2-649): 1.14e-11: 71.2: 8.49
+	Hs
		725139 MYH10_HUMAN (114-762): 2.31e-22: 106: 10.60		ANK2_HUMAN (47-877): 6.14e-50: 195: 12.46