Interactor 1: DDX60 (Q8IY21)
Probable ATP-dependent RNA helicase DDX60 (EC 3.6.4.13) (DEAD box protein 60)
Gene: DDX60

Interactor 2: CGAS (Q8N884)
Cyclic GMP-AMP synthase (cGAMP synthase) (cGAS) (h-cGAS) (EC 2.7.7.86) (2'3'-cGAMP synthase) (Mab-21 domain-containing protein 1)
Gene: CGAS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 30471916
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003690 - double-stranded DNA binding
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0045087 - innate immune response
and 1 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1712
Hs

1 522
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024