Protein: SC6A6
Sodium- and chloride-dependent taurine transporter (Solute carrier family 6 member 6)

Gene: SC6A6, SLC6A6
Organism: Homo sapiens
Interactions: 49
UniProt ID: P31641

Gene Ontology (top 5):
GO:0005283 - amino acid:sodium symporter activity
GO:0005332 - gamma-aminobutyric acid:sodium:chloride symporter activity
GO:0005368 - taurine transmembrane transporter activity
GO:0005369 - taurine:sodium symporter activity
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

375223

RASK
GTPase KRas

3

20

High-throughput

0.640

High

727522

MUC18
Cell surface glycoprotein MUC18

1

5

High-throughput

0.618

High

727530

NHRF3
Na(+)/H(+) exchange regulatory cofactor NHE-RF3

2

20

High-throughput

0.611

High

125265

LEG9
Galectin-9

3

8

High-throughput

0.609

High

727526

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.584

High

379618

IGHA1
Immunoglobulin heavy constant alpha 1

1

2

High-throughput

0.575

High

727548

SC6A5
Sodium- and chloride-dependent glycine transporter 2

1

9

High-throughput

0.575

High

378956

PIGR
Polymeric immunoglobulin receptor

1

0

High-throughput

0.546

High

164904

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

4

High-throughput

0.536

High

727535

AGRG5
Adhesion G-protein coupled receptor G5

1

5

High-throughput

0.536

High

727539

GPR21
Probable G-protein coupled receptor 21

1

4

High-throughput

0.536

High

727541

NMUR2
Neuromedin-U receptor 2

1

2

High-throughput

0.536

High

534693

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.515

High

727537

OR6T1
Olfactory receptor 6T1

1

0

High-throughput

0.513

High

126476

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

189432

STX7
Syntaxin-7

1

15

High-throughput

0.479

High

217880

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.479

High

340990

DIRA3
GTP-binding protein Di-Ras3

1

13

High-throughput

0.479

High

373797

RASN
GTPase NRas

1

20

High-throughput

0.479

High

417279

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

3

High-throughput

0.479

High

463365

LYN
Tyrosine-protein kinase Lyn

1

4

High-throughput

0.479

High

580889

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

727523

RAB5C
Ras-related protein Rab-5C

1

13

High-throughput

0.479

High

727524

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

727527

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

727528

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

727529

STX4
Syntaxin-4

1

15

High-throughput

0.479

High

727536

CXD3
Gap junction delta-3 protein

1

4

High-throughput

0.479

High

727542

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

727543

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

727544

TM216
Transmembrane protein 216

1

3

High-throughput

0.479

High

727545

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

2

High-throughput

0.479

High

727547

LAMP3
Lysosome-associated membrane glycoprotein 3

1

7

High-throughput

0.479

High

71053

PDZ1P
Putative PDZ domain-containing protein PDZK1P1

1

20

High-throughput

0.445

High

424143

S10A8
Protein S100-A8

1

1

High-throughput

0.445

High

727534

MA7D3
MAP7 domain-containing protein 3

1

2

High-throughput

0.445

High

612888

EGR1
Early growth response protein 1

1

1

High-throughput

0.437

High

717376

PDIA3
Protein disulfide-isomerase A3

1

4

High-throughput

0.437

High

727525

RAB2A
Ras-related protein Rab-2A

1

10

High-throughput

0.437

High

727531

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.437

High

727532

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.437

High

727533

TMM17
Transmembrane protein 17

1

3

High-throughput

0.437

High

727538

DDX1
ATP-dependent RNA helicase DDX1

1

0

High-throughput

0.426

High

327556

ELP1
Elongator complex protein 1

1

1

High-throughput

0.407

High

727540

PECR
Peroxisomal trans-2-enoyl-CoA reductase

1

3

High-throughput

0.407

High

714764

EF1D
Elongation factor 1-delta

1

0

High-throughput

0.249

Low

727546

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.249

Low

389968

ALBU
Albumin

1

0

High-throughput

0.232

Low

727549

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025