HitPredict

Interactor 1: ERF3B (Q8IYD1)
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B (Eukaryotic peptide chain release factor subunit 3b) (eRF3b) (EC 3.6.5.-) (G1 to S phase transition protein 2 homolog)
Gene: GSPT2

Interactor 2: RBM14 (Q96PK6)
RNA-binding protein 14 (Paraspeckle protein 2) (PSP2) (RNA-binding motif protein 14) (RRM-containing coactivator activator/modulator) (Synaptotagmin-interacting protein) (SYT-interacting protein)
Gene: RBM14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 628 Hs			1 669
+	Hs
		474030 ERF3B_HUMAN (11-628): 0: 686: 100.00		PAB4L_HUMAN (3-160): 1.38e-35: 140: 21.71
+	Hs
		516584 ERF3B_HUMAN (11-628): 0: 686: 100.00		PABP1_HUMAN (3-538): 5.24e-33: 137: 13.49
+	Hs
		545902 ERF3A_HUMAN (130-628): 0: 570: 93.79		RBM4_HUMAN (1-349): 9.22e-63: 214: 27.22
+	Hs
		1020291 ERF3B_HUMAN (11-628): 0: 686: 100.00		ELAV2_HUMAN (4-154): 1.38e-16: 83.8: 25.15
+	Hs
		1119139 ERF3B_HUMAN (11-628): 0: 686: 100.00		PAP1L_HUMAN (71-151): 4.63e-10: 64.6: 20.23
+	Hs
		1031386 ERF3B_HUMAN (11-628): 0: 686: 100.00		PABP4_HUMAN (71-151): 5.98e-10: 64.2: 23.60
+	Hs
		474004 ERF3A_HUMAN (130-628): 0: 570: 93.79		PAB4L_HUMAN (3-160): 1.38e-35: 140: 21.71
+	Hs
		516347 ERF3A_HUMAN (130-628): 0: 570: 93.79		PABP1_HUMAN (3-538): 5.24e-33: 137: 13.49
+	Hs
		545846 ERF3A_HUMAN (130-628): 0: 570: 93.79		PABP4_HUMAN (71-151): 5.98e-10: 64.2: 23.60
+	Zm
		9835 O50018_MAIZE (197-628): 7.02e-174: 503: 37.70		A0A1D6EZQ5_MAIZE (74-543): 1.93e-24: 109: 12.78