HitPredict

Interactor 1: CD27B (Q8LGU6)
Cell division cycle protein 27 homolog B (CDC27 homolog B) (Protein HOBBIT)
Gene: CDC27B

Interactor 2: APC10 (Q9ZPW2)
Anaphase-promoting complex subunit 10 (APC10) (Cyclosome subunit 10)
Gene: APC10

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.59	1.00	0.770

Property	Details
Experiments	20706207, 17944809
Identification Methods	affinity chromatography technology, two hybrid, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ANAPC10~TPR_1, ANAPC10~TPR_8
Common GO terms	GO:0005680 - anaphase-promoting complex GO:0031145 - anaphase-promoting complex-dependent catabolic process GO:0051301 - cell division
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 744 At			1 192
+	Hs
		1023024 CDC16_HUMAN (433-718): 6.71e-77: 261: 20.81		APC10_HUMAN (19-192): 8.49e-79: 234: 52.30
+	Sc
		743219 CDC27_YEAST (5-738): 5.8e-84: 284: 23.69		APC10_YEAST (20-179): 4.05e-61: 192: 31.88
+	Hs
		1022935 CDC16_HUMAN (433-718): 6.71e-77: 261: 20.81		CUL9_HUMAN (28-190): 5.14e-50: 174: 23.67
+	At
		989584 CD27A_ARATH (481-743): 3.69e-26: 116: 15.85		APC10_ARATH (1-192): 2.43e-88: 259: 100.00
+	At
		71754 CDC16_ARATH (414-670): 9.87e-24: 108: 13.36		APC10_ARATH (1-192): 2.43e-88: 259: 100.00
+	At
		1352813 CDC23_ARATH (274-743): 4.67e-22: 103: 10.64		APC10_ARATH (1-192): 2.43e-88: 259: 100.00
+	Sp
		194972 CUT9_SCHPO (433-719): 1.99e-38: 154: 14.63		APC10_SCHPO (22-192): 1.13e-65: 201: 40.46
+	Hs
		1356117 CDC23_HUMAN (387-741): 5.46e-27: 118: 12.64		APC10_HUMAN (19-192): 8.49e-79: 234: 52.30
+	Sc
		454921 CDC16_YEAST (425-732): 2.1e-39: 158: 19.38		APC10_YEAST (20-179): 4.05e-61: 192: 31.88
+	Hs
		672927 CDC27_HUMAN (12-307): 4.03e-17: 88: 10.20		APC10_HUMAN (19-192): 8.49e-79: 234: 52.30
+	Xl
		1125463 Q6GQ04_XENLA (543-742): 1.64e-14: 79.6: 14.01		Q5EAZ2_XENLA (20-192): 7.05e-79: 235: 53.18
+	Hs
		1219388 CDC23_HUMAN (387-741): 5.46e-27: 118: 12.64		CUL9_HUMAN (28-190): 5.14e-50: 174: 23.67
+	Sp
		194971 APC3_SCHPO (555-742): 5.55e-13: 74.6: 14.89		APC10_SCHPO (22-192): 1.13e-65: 201: 40.46
+	Hs
		672859 CDC27_HUMAN (12-307): 4.03e-17: 88: 10.20		CUL9_HUMAN (28-190): 5.14e-50: 174: 23.67
+	Hs
		1219389 APC7_HUMAN (447-731): 7.77e-17: 86.5: 12.21		CUL9_HUMAN (28-190): 5.14e-50: 174: 23.67
+	Sc
		561124 CDC23_YEAST (12-230): 8.51e-10: 64.2: 8.77		APC10_YEAST (20-179): 4.05e-61: 192: 31.88