HitPredict

Interactor 1: MEN1 (O00255)
Menin
Gene: MEN1

Interactor 2: SET1B (Q9UPS6)
Histone-lysine N-methyltransferase SETD1B (EC 2.1.1.364) (Lysine N-methyltransferase 2G) (SET domain-containing protein 1B) (hSET1B)
Gene: SETD1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0035097 - histone methyltransferase complex
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 610 Hs			1 1966
+	Hs
		123091 MEN1_HUMAN (1-610): 0: 1181: 100.00		KMT2B_HUMAN (1069-1966): 4.68e-71: 268: 21.69
+	Hs
		122981 MEN1_HUMAN (1-610): 0: 1181: 100.00		NSD3_HUMAN (1721-1965): 3.64e-68: 256: 24.90
+	Hs
		122682 MEN1_HUMAN (1-610): 0: 1181: 100.00		KMT2A_HUMAN (1173-1966): 2.68e-66: 252: 21.73
+	Hs
		122888 MEN1_HUMAN (1-610): 0: 1181: 100.00		KMT2C_HUMAN (1759-1966): 1.32e-58: 227: 37.04
+	Hs
		122367 MEN1_HUMAN (1-610): 0: 1181: 100.00		SET1A_HUMAN (409-1966): 1e-54: 214: 22.13
+	Hs
		122360 MEN1_HUMAN (1-610): 0: 1181: 100.00		KMT2D_HUMAN (1826-1966): 3.07e-17: 91.3: 46.85