HitPredict

Interactor 1: MILK1 (Q8N3F8)
MICAL-like protein 1 (Molecule interacting with Rab13) (MIRab13)
Gene: MICALL1

Interactor 2: SH3G1 (Q99961)
Endophilin-A2 (EEN fusion partner of MLL) (Endophilin-2) (Extra eleven-nineteen leukemia fusion gene protein) (EEN) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1)
Gene: SH3GL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045296 - cadherin binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 863 Hs			1 368
+	Hs
		1232328 MILK1_HUMAN (1-863): 1.02e-88: 302: 100.00		PACN1_HUMAN (16-363): 9.35e-37: 139: 14.89
+	Hs
		1232344 MILK1_HUMAN (1-863): 1.02e-88: 302: 100.00		PACN2_HUMAN (16-364): 1.92e-34: 134: 14.97
+	Hs
		1242506 EHBP1_HUMAN (3-833): 2.93e-73: 263: 15.93		PACN1_HUMAN (16-363): 9.35e-37: 139: 14.89
+	Hs
		211580 ACTN4_HUMAN (3-227): 5.94e-64: 233: 29.78		SRC8_HUMAN (35-362): 1.55e-37: 143: 12.16
+	Rn
		555261 ACTN1_RAT (3-227): 5.25e-64: 233: 28.89		SPTN1_RAT (4-365): 2.16e-33: 133: 16.62
+	Hs
		963325 SPTB2_HUMAN (3-246): 8.29e-57: 215: 28.69		SRC8_HUMAN (35-362): 1.55e-37: 143: 12.16
+	Hs
		1045513 SPTN4_HUMAN (4-184): 3.46e-59: 222: 34.81		SPTN1_HUMAN (4-365): 1.47e-33: 134: 15.82
+	Hs
		506818 SPTB1_HUMAN (3-227): 1.88e-58: 220: 28.44		SPTN1_HUMAN (4-365): 1.47e-33: 134: 15.82
+	Hs
		963409 SPTB2_HUMAN (3-246): 8.29e-57: 215: 28.69		PACN1_HUMAN (16-363): 9.35e-37: 139: 14.89
+	Hs
		963320 SPTB2_HUMAN (3-246): 8.29e-57: 215: 28.69		SPTN1_HUMAN (4-365): 1.47e-33: 134: 15.82
+	Rn
		555258 Q6XD99_RAT (3-246): 8.28e-57: 215: 28.69		SPTN1_RAT (4-365): 2.16e-33: 133: 16.62
+	Hs
		164614 SPTN2_HUMAN (3-246): 1.43e-54: 208: 29.92		SPTN1_HUMAN (4-365): 1.47e-33: 134: 15.82
+	Hs
		298946 ACTN1_HUMAN (3-227): 1.28e-64: 235: 29.78		SRBS2_HUMAN (270-363): 9.46e-12: 68.6: 23.96
+	Mm
		1113251 ACTN1_MOUSE (3-227): 4.82e-64: 233: 29.33		SRBS2_MOUSE (270-363): 5.94e-12: 69.3: 22.92
+	Hs
		211443 ACTN4_HUMAN (3-227): 5.94e-64: 233: 29.78		SRBS2_HUMAN (270-363): 9.46e-12: 68.6: 23.96
+	Hs
		521521 ACTN1_HUMAN (3-227): 1.28e-64: 235: 29.78		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		211557 ACTN4_HUMAN (3-227): 5.94e-64: 233: 29.78		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Ce
		110517 H2L2C8_CAEEL (3-224): 2.23e-61: 225: 30.63		SEM5_CAEEL (312-360): 2.06e-11: 65.1: 55.10
+	Ce
		666217 Q23158_CAEEL (3-224): 9.69e-59: 218: 27.27		SEM5_CAEEL (312-360): 2.06e-11: 65.1: 55.10
+	Hs
		924482 SPTB2_HUMAN (3-246): 8.29e-57: 215: 28.69		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38