HitPredict

Interactor 1: STAG2 (Q8N3U4)
Cohesin subunit SA-2 (SCC3 homolog 2) (Stromal antigen 2)
Gene: STAG2

Interactor 2: PDS5B (Q9NTI5)
Sister chromatid cohesion protein PDS5 homolog B (Androgen-induced proliferation inhibitor) (Androgen-induced prostate proliferative shutoff-associated protein AS3)
Gene: PDS5B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.709

Property	Details
Experiments	31010829, 35271311, 17113138, 15855230, 29867216
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000775 - chromosome, centromeric region GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005694 - chromosome and 2 others more... GO:0005829 - cytosol GO:0051301 - cell division
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1231 Hs			1 1447
+	Mm
		93877 STAG2_MOUSE (1-1231): 0: 1728: 99.11		E9QPI5_MOUSE (2-1351): 0: 1435: 67.48
+	Hs
		1100532 STAG2_HUMAN (1-1231): 0: 1716: 100.00		PDS5A_HUMAN (2-1362): 0: 1442: 66.94
+	Hs
		1261586 STAG1_HUMAN (6-1231): 0: 1584: 69.85		PDS5B_HUMAN (1-1424): 0: 1569: 100.00
+	Xl
		1115497 Q5XGV2_XENLA (1-1231): 0: 1661: 85.71		PD5BA_XENLA (1-1446): 0: 1478: 84.22
+	Xl
		1115500 STAG2_XENLA (70-1231): 0: 1616: 88.58		PD5BA_XENLA (1-1446): 0: 1478: 84.22
+	Xl
		1117308 Q5XGV2_XENLA (1-1231): 0: 1661: 85.71		PD5AB_XENLA (13-1350): 0: 1403: 66.99
+	Hs
		1100541 STAG1_HUMAN (6-1231): 0: 1584: 69.85		PDS5A_HUMAN (2-1362): 0: 1442: 66.94
+	Xl
		1115501 STAG1_XENLA (6-1231): 0: 1541: 67.92		PD5BA_XENLA (1-1446): 0: 1478: 84.22
+	Xl
		1117311 STAG2_XENLA (70-1231): 0: 1616: 88.58		PD5AB_XENLA (13-1350): 0: 1403: 66.99
+	Xl
		1118108 STAG2_XENLA (70-1231): 0: 1616: 88.58		PD5AA_XENLA (4-1350): 0: 1402: 66.57
+	Xl
		1118109 STAG1_XENLA (6-1231): 0: 1541: 67.92		PD5AA_XENLA (4-1350): 0: 1402: 66.57
+	Dm
		53422 Q9VM62_DROME (41-1074): 0: 1140: 44.86		A1Z8S6_DROME (11-1191): 0: 1122: 35.51
+	Hs
		69119 STAG2_HUMAN (1-1231): 0: 1716: 100.00		A9IYQ1_HUMAN (1047-1350): 1.04e-39: 151: 99.34
+	Mm
		193220 STAG2_MOUSE (1-1231): 0: 1728: 99.11		NIPBL_MOUSE (1029-1447): 7.86e-17: 89.2: 11.57
+	Hs
		1154052 STAG2_HUMAN (1-1231): 0: 1716: 100.00		NIPBL_HUMAN (1008-1443): 5.96e-17: 89.6: 11.11
+	Hs
		69120 STAG1_HUMAN (6-1231): 0: 1584: 69.85		A9IYQ1_HUMAN (1047-1350): 1.04e-39: 151: 99.34
+	Hs
		1154057 STAG1_HUMAN (6-1231): 0: 1584: 69.85		NIPBL_HUMAN (1008-1443): 5.96e-17: 89.6: 11.11
+	Sc
		775349 SCC3_YEAST (40-419): 4.79e-90: 317: 24.69		PDS5_YEAST (6-1216): 0: 851: 19.02