Protein: SFR19
Splicing factor, arginine/serine-rich 19 (SR-related C-terminal domain-associated factor 1) (SR-related and CTD-associated factor 1) (SR-related-CTD-associated factor) (SCAF) (Serine arginine-rich pre-mRNA splicing factor SR-A1) (SR-A1)

Gene: SFR19, SCAF1
Organism: Homo sapiens
Interactions: 136
UniProt ID: Q9H7N4

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0006366 - transcription by RNA polymerase II
GO:0006397 - mRNA processing
GO:0008380 - RNA splicing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

976151

RPB7
DNA-directed RNA polymerase II subunit RPB7

5

1

High-throughput

0.712

High

1006717

SRPK2
SRSF protein kinase 2

4

20

High-throughput

0.694

High

898824

RL14
Large ribosomal subunit protein eL14

3

4

High-throughput

0.667

High

1418588

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

3

11

High-throughput

0.667

High

208384

RRP8
Ribosomal RNA-processing protein 8

2

1

High-throughput

0.628

High

473088

RU17
U1 small nuclear ribonucleoprotein 70 kDa

2

10

High-throughput

0.628

High

517707

ZBT48
Zinc finger and BTB domain-containing protein 48

2

1

High-throughput

0.628

High

649426

H1T
Histone H1t

2

15

High-throughput

0.628

High

685731

U2AF2
Splicing factor U2AF 65 kDa subunit

2

14

High-throughput

0.628

High

1239667

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

2

4

High-throughput

0.628

High

1416121

RBM4
RNA-binding protein 4

2

9

High-throughput

0.628

High

1432355

PININ
Pinin

2

3

High-throughput

0.628

High

134869

SAP18
Histone deacetylase complex subunit SAP18

2

3

High-throughput

0.611

High

502538

H2A1
Histone H2A type 1

2

12

High-throughput

0.611

High

912234

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

2

3

High-throughput

0.611

High

192396

GSC2
Homeobox protein goosecoid-2

2

10

High-throughput

0.606

High

1435878

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

2

10

High-throughput

0.601

High

373160

MYC
Myc proto-oncogene protein

2

16

High-throughput

0.584

High

621749

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

6

High-throughput

0.584

High

1407514

CIB1
Calcium and integrin-binding protein 1

2

0

High-throughput

0.580

High

1256737

NKAP1
Uncharacterized protein NKAPD1

2

2

High-throughput

0.574

High

396959

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

1260479

MTSS2
Protein MTSS 2

2

5

High-throughput

0.553

High

192856

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

1

High-throughput

0.536

High

256684

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

9

High-throughput

0.536

High

390183

ALBU
Albumin

1

1

High-throughput

0.536

High

428988

RLA0
Large ribosomal subunit protein uL10

1

3

High-throughput

0.536

High

447455

NPM
Nucleophosmin

1

4

High-throughput

0.536

High

521943

H14
Histone H1.4

1

15

High-throughput

0.536

High

542224

TOP1
DNA topoisomerase 1

1

5

High-throughput

0.536

High

595596

H15
Histone H1.5

1

15

High-throughput

0.536

High

596358

H12
Histone H1.2

1

15

High-throughput

0.536

High

615987

RL17
Large ribosomal subunit protein uL22

1

2

High-throughput

0.536

High

621969

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

2

High-throughput

0.536

High

658410

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.536

High

693983

RL10
Large ribosomal subunit protein uL16

1

6

High-throughput

0.536

High

860005

RL28
Large ribosomal subunit protein eL28

1

1

High-throughput

0.536

High

860951

RS10
Small ribosomal subunit protein eS10

1

3

High-throughput

0.536

High

1008891

RED1
Double-stranded RNA-specific editase 1

1

14

High-throughput

0.536

High

1009323

PRR3
Proline-rich protein 3

1

1

High-throughput

0.536

High

1016233

RL19
Large ribosomal subunit protein eL19

1

1

High-throughput

0.536

High

1016615

SRSF3
Serine/arginine-rich splicing factor 3

1

20

High-throughput

0.536

High

1061151

SRSF1
Serine/arginine-rich splicing factor 1

1

20

High-throughput

0.536

High

1062114

SRSF4
Serine/arginine-rich splicing factor 4

1

20

High-throughput

0.536

High

1065432

SSRP1
FACT complex subunit SSRP1

1

15

High-throughput

0.536

High

1099254

SRSF5
Serine/arginine-rich splicing factor 5

1

20

High-throughput

0.536

High

1099538

SRSF6
Serine/arginine-rich splicing factor 6

1

20

High-throughput

0.536

High

1151199

OASL
2'-5'-oligoadenylate synthase-like protein

1

6

High-throughput

0.536

High

1160083

SRSF7
Serine/arginine-rich splicing factor 7

1

20

High-throughput

0.536

High

1233215

THOC7
THO complex subunit 7

1

1

High-throughput

0.536

High

1252519

LN28B
Protein lin-28 homolog B

1

6

High-throughput

0.536

High

1365672

LAR4B
La-related protein 4B

1

1

High-throughput

0.536

High

1390973

THOC1
THO complex subunit 1

1

1

High-throughput

0.536

High

1399352

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

8

High-throughput

0.536

High

1435876

LN28A
Protein lin-28 homolog A

1

6

High-throughput

0.536

High

1435884

PURG
Purine-rich element-binding protein gamma

1

1

High-throughput

0.536

High

1435885

RALY
RNA-binding protein Raly

1

4

High-throughput

0.536

High

1435887

ABT1
Activator of basal transcription 1

1

3

High-throughput

0.536

High

1435888

RL36
Large ribosomal subunit protein eL36

1

3

High-throughput

0.536

High

833560

BUD31
Protein BUD31 homolog

1

0

High-throughput

0.518

High

1232579

Q6FHY5
MEOX2 protein

1

3

High-throughput

0.515

High

1435879

UBQL4
Ubiquilin-4

1

6

High-throughput

0.508

High

508638

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

7

High-throughput

0.501

High

1127496

FGFP1
Fibroblast growth factor-binding protein 1

1

1

High-throughput

0.489

High

894169

MEOX2
Homeobox protein MOX-2

1

3

High-throughput

0.481

High

130616

SPT5H
Transcription elongation factor SPT5

1

9

High-throughput

0.479

High

256988

H2B1K
Histone H2B type 1-K

1

20

High-throughput

0.479

High

262571

MCE1
mRNA-capping enzyme

1

4

High-throughput

0.479

High

316320

RECQ5
ATP-dependent DNA helicase Q5

1

15

High-throughput

0.479

High

326374

SCAF4
SR-related and CTD-associated factor 4

1

7

High-throughput

0.479

High

346337

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

18

High-throughput

0.479

High

401490

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

10

High-throughput

0.479

High

406649

MYCN
N-myc proto-oncogene protein

1

14

High-throughput

0.479

High

487761

PARP1
Poly [ADP-ribose] polymerase 1

1

17

High-throughput

0.479

High

504979

H2AB2
Histone H2A-Bbd type 2/3

1

14

High-throughput

0.479

High

589701

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.479

High

667457

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

High-throughput

0.479

High

673958

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.479

High

696520

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.479

High

723092

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

3

High-throughput

0.479

High

787789

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

1

High-throughput

0.479

High

912127

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

1

High-throughput

0.479

High

946884

H2B1D
Histone H2B type 1-D

1

20

High-throughput

0.479

High

980331

H4
Histone H4

1

10

High-throughput

0.479

High

981100

H2B1C
Histone H2B type 1-C/E/F/G/I

1

20

High-throughput

0.479

High

983706

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

1

High-throughput

0.479

High

984992

RL31
Large ribosomal subunit protein eL31

1

1

High-throughput

0.479

High

986217

RL8
Large ribosomal subunit protein uL2

1

1

High-throughput

0.479

High

1045773

TF65
Transcription factor p65

1

13

High-throughput

0.479

High

1085620

FOXO1
Forkhead box protein O1

1

8

High-throughput

0.479

High

1128115

DHX8
ATP-dependent RNA helicase DHX8

1

11

High-throughput

0.479

High

1141309

BRD3
Bromodomain-containing protein 3

1

18

High-throughput

0.479

High

1217614

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

1

18

High-throughput

0.479

High

1270333

SPT6H
Transcription elongation factor SPT6

1

2

High-throughput

0.479

High

1311860

DHX40
Probable ATP-dependent RNA helicase DHX40

1

11

High-throughput

0.479

High

1313049

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

1

1

High-throughput

0.479

High

1334927

SERB1
SERPINE1 mRNA-binding protein 1

1

6

High-throughput

0.479

High

1346933

SNIP1
Smad nuclear-interacting protein 1

1

6

High-throughput

0.479

High

1367286

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1368622

KAT6A
Histone acetyltransferase KAT6A

1

14

High-throughput

0.479

High

1372308

H2B1H
Histone H2B type 1-H

1

20

High-throughput

0.479

High

1387562

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

20

High-throughput

0.479

High

1408053

H2B1L
Histone H2B type 1-L

1

20

High-throughput

0.479

High

1414572

DDX23
Probable ATP-dependent RNA helicase DDX23

1

11

High-throughput

0.479

High

1435880

RAD18
E3 ubiquitin-protein ligase RAD18

1

4

High-throughput

0.479

High

1435881

TECR
Very-long-chain enoyl-CoA reductase

1

1

High-throughput

0.479

High

1435883

ZRAN1
Ubiquitin thioesterase ZRANB1

1

12

High-throughput

0.479

High

1105660

GOGA4
Golgin subfamily A member 4

1

18

High-throughput

0.470

High

479872

GSTP1
Glutathione S-transferase P

1

0

High-throughput

0.460

High

688153

EF1G
Elongation factor 1-gamma

1

0

High-throughput

0.458

High

923539

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.458

High

1368758

SYMPK
Symplekin

1

0

High-throughput

0.458

High

288774

NPM3
Nucleoplasmin-3

1

4

High-throughput

0.445

High

686436

RL13
Large ribosomal subunit protein eL13

1

4

High-throughput

0.445

High

807585

IF4A3
Eukaryotic initiation factor 4A-III

1

11

High-throughput

0.445

High

1337418

SRFB1
Serum response factor-binding protein 1

1

1

High-throughput

0.445

High

157859

CTRO
Citron Rho-interacting kinase

1

10

High-throughput

0.437

High

272468

OBSL1
Obscurin-like protein 1

1

14

High-throughput

0.437

High

769191

RFA3
Replication protein A 14 kDa subunit

1

7

High-throughput

0.437

High

879466

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

14

High-throughput

0.437

High

1127986

KPRA
Phosphoribosyl pyrophosphate synthase-associated protein 1

1

1

High-throughput

0.437

High

1220806

RN123
E3 ubiquitin-protein ligase RNF123

1

14

High-throughput

0.437

High

1232019

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

1

1

High-throughput

0.437

High

1235526

IFIX
Pyrin and HIN domain-containing protein 1

1

7

High-throughput

0.437

High

1328958

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

6

High-throughput

0.437

High

1338964

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.437

High

1435877

GPN1
GPN-loop GTPase 1

1

1

High-throughput

0.437

High

1435882

PHRF1
PHD and RING finger domain-containing protein 1

1

19

High-throughput

0.437

High

379308

IGHG1
Immunoglobulin heavy constant gamma 1

1

2

High-throughput

0.407

High

1396580

C170L
Cep170-like protein

1

3

High-throughput

0.407

High

1359807

RT4I1
NAD(P)H oxidoreductase RTN4IP1, mitochondrial

2

0

High-throughput

0.316

High

1357265

CHAC2
Glutathione-specific gamma-glutamylcyclotransferase 2

1

0

High-throughput

0.279

Low

1435886

PAI2B
Polyadenylate-binding protein-interacting protein 2B

1

0

High-throughput

0.279

Low

914344

EFNA4
Ephrin-A4

1

0

High-throughput

0.249

Low

1420613

IN80B
INO80 complex subunit B

1

0

High-throughput

0.249

Low

506028

GRL1A
DNA-directed RNA polymerase II subunit GRINL1A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025