HitPredict

Interactor 1: LTOR1 (Q6IAA8)
Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18) (Protein associated with DRMs and endosomes) (p27Kip1-releasing factor from RhoA) (p27RF-Rho)
Gene: LAMTOR1

Interactor 2: VAMP8 (Q9BV40)
Vesicle-associated membrane protein 8 (VAMP-8) (Endobrevin) (EDB)
Gene: VAMP8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005765 - lysosomal membrane GO:0005886 - plasma membrane GO:0031902 - late endosome membrane GO:0035577 - azurophil granule membrane GO:0035579 - specific granule membrane and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 161 Hs			1 100
+	Hs
		908020 LTOR1_HUMAN (1-161): 1.94e-90: 262: 100.00		VAMP7_HUMAN (1-100): 1.48e-26: 98.8: 38.00
+	Hs
		278515 LTOR1_HUMAN (1-161): 1.94e-90: 262: 100.00		VAMP4_HUMAN (7-80): 6.44e-25: 92.6: 29.73
+	Hs
		1154646 LTOR1_HUMAN (1-161): 1.94e-90: 262: 100.00		VAMP3_HUMAN (9-79): 6.57e-24: 88.8: 36.62
+	Hs
		989344 LTOR1_HUMAN (1-161): 1.94e-90: 262: 100.00		VAMP2_HUMAN (6-82): 1.81e-23: 88: 35.07