HitPredict

Interactor 1: LZTR1 (Q8N653)
Leucine-zipper-like transcriptional regulator 1 (LZTR-1)
Gene: LZTR1

Interactor 2: KBTB4 (Q9NVX7)
Kelch repeat and BTB domain-containing protein 4 (BTB and kelch domain-containing protein 4)
Gene: KBTBD4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.726

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BACK~BTB, BTB~BTB
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 840 Hs			1 518
+	Hs
		848302 HCFC1_HUMAN (104-467): 7.65e-45: 177: 17.16		KBTB4_HUMAN (1-518): 1.75e-117: 358: 100.00
+	Dr
		1092565 KEP1A_DANRE (625-837): 2.73e-45: 174: 18.43		KEP1A_DANRE (5-517): 4.85e-111: 343: 18.14
+	Hs
		1348052 KLH28_HUMAN (224-524): 1.62e-35: 144: 14.11		KLHL9_HUMAN (21-517): 4.37e-114: 352: 18.03
+	Hs
		1348053 KLH28_HUMAN (224-524): 1.62e-35: 144: 14.11		KLH13_HUMAN (21-517): 3.17e-113: 351: 18.41
+	Hs
		152490 KEAP1_HUMAN (236-481): 2.95e-30: 129: 13.44		ENC1_HUMAN (19-518): 3.57e-105: 328: 17.93
+	Dm
		1374538 KLHDB_DROME (632-837): 2.74e-54: 200: 21.85		KLHDB_DROME (189-429): 1.8e-32: 133: 15.51
+	Dm
		1366016 Q9VGE5_DROME (185-481): 2.18e-50: 188: 14.77		Q9VGE5_DROME (117-429): 1.93e-32: 132: 12.92
+	Hs
		1348057 KLH28_HUMAN (224-524): 1.62e-35: 144: 14.11		IPP_HUMAN (17-472): 1.06e-42: 162: 13.07
+	Hs
		1299557 KLHL5_HUMAN (4-237): 5.73e-40: 160: 20.94		KLHL1_HUMAN (86-429): 2.92e-35: 142: 12.74
+	Hs
		1299555 KLHL5_HUMAN (4-237): 5.73e-40: 160: 20.94		KLHL4_HUMAN (105-429): 1.19e-34: 140: 12.09
+	Hs
		1319382 KLHL1_HUMAN (238-525): 1.38e-39: 159: 13.75		KLHL4_HUMAN (105-429): 1.19e-34: 140: 12.09
+	Hs
		1153780 KLH10_HUMAN (650-837): 9.12e-47: 179: 21.16		KLH10_HUMAN (168-430): 2.2e-25: 111: 12.73
+	Hs
		307172 KEAP1_HUMAN (236-481): 2.95e-30: 129: 13.44		KLHL2_HUMAN (209-474): 4.63e-42: 160: 17.33
+	Mm
		1378292 KEAP1_MOUSE (236-481): 3.14e-30: 129: 11.86		KEAP1_MOUSE (210-427): 1.8e-33: 136: 19.37
+	Hs
		1049204 KEAP1_HUMAN (236-481): 2.95e-30: 129: 13.44		KEAP1_HUMAN (210-427): 5.91e-33: 134: 19.37
+	Mm
		1164599 KLH17_MOUSE (218-456): 1.7e-31: 133: 13.75		KLH17_MOUSE (265-429): 2e-27: 118: 17.16
+	Hs
		1121499 KLH28_HUMAN (224-524): 1.62e-35: 144: 14.11		KLH26_HUMAN (172-426): 3.12e-22: 102: 15.87
+	Hs
		1348055 KLH28_HUMAN (224-524): 1.62e-35: 144: 14.11		KLH21_HUMAN (21-222): 2.97e-20: 96.3: 30.58
+	Hs
		1164628 KLH28_HUMAN (224-524): 1.62e-35: 144: 14.11		KLH24_HUMAN (84-431): 2.48e-19: 93.4: 12.95