Interactor 1: ANM5 (Q6NUA1)
Protein arginine N-methyltransferase 5 (prmt5) (EC 2.1.1.320) (Histone synthetic lethal 7 protein) (Hsl7) (Histone-arginine N-methyltransferase PRMT5)
Gene: prmt5
Interactor 2: MEP50 (Q6NUD0)
Methylosome protein WDR77 (Methylosome protein 50) (MEP-50) (WD repeat-containing protein 77)
Gene: wdr77
Species: Xenopus laevis
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.54 | 1.00 | 0.740 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23451136 |
| Identification Methods | x-ray crystallography, molecular sieving, static light scattering, cosedimentation in solution, x ray scattering |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PRMT5~WD40, PRMT5_TIM~WD40 |
| Common GO terms | GO:0005829 - cytosol GO:0034709 - methylosome |
| Homologous interactions | 10 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
