Protein: ANM5
Protein arginine N-methyltransferase 5 (Prmt5) (EC 2.1.1.320) (Histone-arginine N-methyltransferase PRMT5) (Jak-binding protein 1) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog)

Gene: ANM5, Prmt5
Organism: Mus musculus
Interactions: 31
UniProt ID: Q8CIG8

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000387 - spliceosomal snRNP assembly
GO:0001673 - male germ cell nucleus
GO:0003682 - chromatin binding
GO:0003714 - transcription corepressor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1298737

MEP50
Methylosome protein WDR77

2

11

Small-scale

0.759

High

1297715

A16L1
Autophagy-related protein 16-1

1

9

High-throughput

0.618

High

1298738

CHTOP
Chromatin target of PRMT1 protein

1

4

Small-scale

0.603

High

1298736

EED
Polycomb protein EED

1

8

Small-scale

0.575

High

1189462

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

2

4

Small-scale

0.571

High

1223909

NR0B2
Nuclear receptor subfamily 0 group B member 2

1

8

Small-scale

0.561

High

671897

CCND1
G1/S-specific cyclin-D1

1

2

Small-scale

0.536

High

1240108

HDAC4
Histone deacetylase 4

1

5

High-throughput

0.536

High

690159

RSMB
Small nuclear ribonucleoprotein-associated protein B

1

5

Small-scale

0.501

High

710998

PABP1
Polyadenylate-binding protein 1

1

8

Small-scale

0.501

High

1221298

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

20

Small-scale

0.501

High

1223924

RU1C
U1 small nuclear ribonucleoprotein C

1

1

Small-scale

0.501

High

1298735

SF3B4
Splicing factor 3B subunit 4

1

12

Small-scale

0.501

High

1298739

SERB1
SERPINE1 mRNA-binding protein 1

1

7

Small-scale

0.501

High

518522

MYOD1
Myoblast determination protein 1

1

4

Small-scale

0.479

High

687565

PGFRA
Platelet-derived growth factor receptor alpha

1

1

Small-scale

0.479

High

867723

GLI1
Zinc finger protein GLI1

1

5

Small-scale

0.479

High

927917

ATX1
Ataxin-1

1

1

High-throughput

0.479

High

1021870

CRY1
Cryptochrome-1

1

2

Small-scale

0.479

High

1223805

JAK3
Tyrosine-protein kinase JAK3

1

9

Small-scale

0.479

High

1223826

TRI27
Zinc finger protein RFP

1

3

Small-scale

0.479

High

1282232

FACD2
Fanconi anemia group D2 protein homolog

1

2

High-throughput

0.479

High

1283137

NANOG
Homeobox protein NANOG

1

4

High-throughput

0.479

High

1298740

GANP
Germinal-center associated nuclear protein

1

6

Small-scale

0.479

High

648067

MYD88
Myeloid differentiation primary response protein MyD88

1

0

Small-scale

0.458

High

1222492

SAP
Prosaposin

1

0

High-throughput

0.458

High

1298566

TCRG1
Transcription elongation regulator 1

1

6

Small-scale

0.457

High

718979

CDK4
Cyclin-dependent kinase 4

1

4

Small-scale

0.445

High

915706

HMGA2
High mobility group protein HMGI-C

1

1

High-throughput

0.445

High

949078

RUVB1
RuvB-like 1

1

2

Small-scale

0.445

High

1296099

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

1

High-throughput

0.437

High


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Last updated: 11Aug2025