HitPredict

Interactor 1: NUP43 (Q8NFH3)
Nucleoporin Nup43 (Nup107-160 subcomplex subunit Nup43) (p42)
Gene: NUP43

Interactor 2: SPAST (Q9UBP0)
Spastin (EC 5.6.1.1) (Spastic paraplegia 4 protein)
Gene: SPAST

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 616
+	Hs
		907118 FBXW7_HUMAN (3-371): 2.85e-70: 235: 12.30		PRS8_HUMAN (224-608): 1.29e-110: 339: 26.26
+	Sc
		630852 NLE1_YEAST (106-378): 3.19e-57: 196: 11.18		AFG2_YEAST (9-615): 7.17e-118: 370: 21.37
+	Hs
		903094 WDR5_HUMAN (3-289): 4.3e-58: 193: 14.24		PRS10_HUMAN (278-605): 4.34e-113: 345: 29.64
+	Hs
		903081 WDR5_HUMAN (3-289): 4.3e-58: 193: 14.24		PRS8_HUMAN (224-608): 1.29e-110: 339: 26.26
+	Hs
		792951 LIS1_HUMAN (5-248): 1.25e-48: 171: 12.06		PRS8_HUMAN (224-608): 1.29e-110: 339: 26.26
+	Hs
		1126087 SNR40_HUMAN (249-378): 1.1e-25: 107: 17.04		FIGN_HUMAN (182-612): 5.97e-115: 362: 28.54
+	Ce
		954109 LIN53_CAEEL (216-378): 1.44e-20: 94.1: 14.29		PRS8_CAEEL (191-608): 8.84e-113: 345: 24.30
+	Ce
		873008 LIN53_CAEEL (216-378): 1.44e-20: 94.1: 14.29		TERA2_CAEEL (323-616): 2.94e-75: 258: 29.61
+	Ce
		872993 LIN53_CAEEL (216-378): 1.44e-20: 94.1: 14.29		TERA1_CAEEL (323-616): 3.37e-75: 257: 29.61
+	Sp
		251185 WAT1_SCHPO (144-295): 4.72e-15: 77.2: 21.05		CDC48_SCHPO (305-616): 3.38e-79: 268: 31.27
+	Hs
		874768 WDR5_HUMAN (3-289): 4.3e-58: 193: 14.24		TERA_HUMAN (8-346): 2.68e-20: 97.3: 8.86
+	Hs
		875263 GRWD1_HUMAN (68-330): 6.16e-56: 191: 15.84		TERA_HUMAN (8-346): 2.68e-20: 97.3: 8.86
+	Hs
		265395 LIS1_HUMAN (5-248): 1.25e-48: 171: 12.06		KTNA1_HUMAN (57-255): 6.43e-12: 70: 12.22
+	Hs
		875215 SNR40_HUMAN (249-378): 1.1e-25: 107: 17.04		TERA_HUMAN (8-346): 2.68e-20: 97.3: 8.86
+	Hs
		196980 PRP4_HUMAN (215-379): 1.68e-23: 103: 17.71		TERA_HUMAN (8-346): 2.68e-20: 97.3: 8.86
+	Xl
		1001507 KTNB1_XENLA (144-293): 1.11e-12: 71.4: 23.33		Q0IHC2_XENLA (57-297): 7.95e-12: 70: 12.17