Interactor 1: THOC2 (Q8NI27)
THO complex subunit 2 (Tho2) (hTREX120)
Gene: THOC2

Interactor 2: THOC1 (Q96FV9)
THO complex subunit 1 (Tho1) (Nuclear matrix protein p84) (p84N5) (hTREX84)
Gene: THOC1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 26496610, 28514442, 29395067, 33961781, 15998806, 17190602, 23222130, 19165146
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Tho2~efThoc1, Thoc2~efThoc1, THOC2_N~efThoc1
Common GO terms GO:0000346 - transcription export complex
GO:0000347 - THO complex
GO:0000445 - THO complex part of transcription export complex
GO:0005654 - nucleoplasm
GO:0006397 - mRNA processing
and 3 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1593
Hs

1 657
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024