Protein: RRP43
Exosome complex component RRP43 (Ribosomal RNA-processing protein 43)

Gene: RRP43
Organism: Saccharomyces cerevisiae S288C
Interactions: 164
UniProt ID: P25359

Gene Ontology (top 5):
GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

630276

RRP44
Exosome complex exonuclease DIS3

12

1

Small-scale

0.981

High

630229

RRP46
Exosome complex component RRP46

12

2

Small-scale

0.980

High

630218

RRP41
Exosome complex component SKI6

9

2

Small-scale

0.970

High

630257

RRP45
Exosome complex component RRP45

8

2

Small-scale

0.967

High

630237

CSL4
Exosome complex component CSL4

10

0

Small-scale

0.923

High

630193

RRP4
Exosome complex component RRP4

6

0

Small-scale

0.895

High

630223

MTR3
Exosome complex component MTR3

5

0

Small-scale

0.872

High

630279

RRP40
Exosome complex component RRP40

3

0

High-throughput

0.803

High

630255

RRP5
rRNA biogenesis protein RRP5

3

0

High-throughput

0.775

High

630289

RRP6
Exosome complex exonuclease RRP6

12

0

Small-scale

0.724

High

630294

RRP42
Exosome complex component RRP42

5

2

Small-scale

0.712

High

630282

SKI7
Superkiller protein 7

7

0

Small-scale

0.712

High

630235

MPP6
M-phase phosphoprotein 6 homolog

4

0

Small-scale

0.662

High

630284

NIP7
60S ribosome subunit biogenesis protein NIP7

3

0

Small-scale

0.648

High

630194

LRP1
Exosome complex protein LRP1

4

0

Small-scale

0.648

High

621982

SSD1
Protein SSD1

1

1

High-throughput

0.618

High

630165

KRR1
KRR1 small subunit processome component

3

0

High-throughput

0.613

High

630190

ENP1
Essential nuclear protein 1

3

0

High-throughput

0.613

High

630213

UTP10
U3 small nucleolar RNA-associated protein 10

3

0

High-throughput

0.613

High

630250

DHR1
Probable ATP-dependent RNA helicase DHR1

3

0

High-throughput

0.613

High

630179

SKI2
Antiviral helicase SKI2

2

3

High-throughput

0.601

High

630219

MTR4
ATP-dependent RNA helicase DOB1

2

3

High-throughput

0.601

High

630245

IMA1
Importin subunit alpha

2

0

High-throughput

0.595

High

630160

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.586

High

630217

ROK1
ATP-dependent RNA helicase ROK1

2

2

High-throughput

0.584

High

630267

NOC4
Nucleolar complex protein 4

2

2

High-throughput

0.584

High

571874

SKI3
Superkiller protein 3

2

0

High-throughput

0.559

High

630196

UTP9
U3 small nucleolar RNA-associated protein 9

2

0

High-throughput

0.559

High

630228

UTP22
U3 small nucleolar RNA-associated protein 22

2

0

High-throughput

0.559

High

630238

NOP13
Nucleolar protein 13

2

0

High-throughput

0.559

High

630239

NAT10
RNA cytidine acetyltransferase

2

0

High-throughput

0.559

High

630253

UTP14
U3 small nucleolar RNA-associated protein 14

2

0

High-throughput

0.559

High

630285

BMS1
Ribosome biogenesis protein BMS1

2

0

High-throughput

0.559

High

630288

SAS10
Something about silencing protein 10

2

0

High-throughput

0.559

High

630300

NOP14
Nucleolar complex protein 14

2

0

High-throughput

0.559

High

630191

PIH1
Protein interacting with Hsp90 1

1

0

Small-scale

0.549

High

630195

BZZ1
Protein BZZ1

1

0

High-throughput

0.518

High

630233

NRD1
Protein NRD1

1

0

Small-scale

0.513

High

630175

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.493

High

630181

MYO3
Myosin-3

1

0

High-throughput

0.493

High

630227

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

High-throughput

0.493

High

630234

PAP2
Poly(A) RNA polymerase protein 2

1

0

High-throughput

0.493

High

630188

HMT1
Protein arginine N-methyltransferase 1

1

0

Small-scale

0.480

High

630287

NOP53
Ribosome biogenesis protein NOP53

1

0

Small-scale

0.480

High

548355

MS116
ATP-dependent RNA helicase MSS116, mitochondrial

1

4

High-throughput

0.479

High

593499

DBP3
ATP-dependent RNA helicase DBP3

1

1

High-throughput

0.479

High

593587

DBP4
ATP-dependent RNA helicase HCA4

1

2

High-throughput

0.479

High

624026

DBP2
ATP-dependent RNA helicase DBP2

1

1

High-throughput

0.479

High

630166

PWP2
Periodic tryptophan protein 2

1

1

High-throughput

0.479

High

630170

RENT1
ATP-dependent helicase NAM7

1

1

High-throughput

0.479

High

630189

MAK5
ATP-dependent RNA helicase MAK5

1

2

High-throughput

0.479

High

630225

CLA4
Serine/threonine-protein kinase CLA4

1

1

High-throughput

0.479

High

630231

SLH1
RQC trigger complex helicase SLH1

1

2

High-throughput

0.479

High

630236

DBP6
ATP-dependent RNA helicase DBP6

1

3

High-throughput

0.479

High

630240

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

1

High-throughput

0.479

High

630241

SEN1
Helicase SEN1

1

1

High-throughput

0.479

High

630244

SKI8
Antiviral protein SKI8

1

2

High-throughput

0.479

High

630247

UTP17
NET1-associated nuclear protein 1

1

3

High-throughput

0.479

High

630248

HAS1
ATP-dependent RNA helicase HAS1

1

3

High-throughput

0.479

High

630249

UTP5
U3 small nucleolar RNA-associated protein 5

1

1

High-throughput

0.479

High

630256

FCF1
rRNA-processing protein FCF1

1

1

High-throughput

0.479

High

630258

UTP13
U3 small nucleolar RNA-associated protein 13

1

1

High-throughput

0.479

High

630259

UTP21
U3 small nucleolar RNA-associated protein 21

1

2

High-throughput

0.479

High

630261

JIP5
WD repeat-containing protein JIP5

1

1

High-throughput

0.479

High

630262

DBP9
ATP-dependent RNA helicase DBP9

1

1

High-throughput

0.479

High

630269

UTP4
U3 small nucleolar RNA-associated protein 4

1

1

High-throughput

0.479

High

630272

NOC3
Nucleolar complex-associated protein 3

1

1

High-throughput

0.479

High

630277

BRX1
Ribosome biogenesis protein BRX1

1

2

High-throughput

0.479

High

630291

MAK21
Ribosome biogenesis protein MAK21

1

2

High-throughput

0.479

High

630292

UTP12
U3 small nucleolar RNA-associated protein 12

1

2

High-throughput

0.479

High

630295

UTP23
rRNA-processing protein UTP23

1

1

High-throughput

0.479

High

630296

DBP10
ATP-dependent RNA helicase DBP10

1

1

High-throughput

0.479

High

630297

NOP56
Nucleolar protein 56

1

1

High-throughput

0.479

High

630298

NOP58
Nucleolar protein 58

1

1

High-throughput

0.479

High

405451

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

408282

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

410487

CYSD
Homocysteine/cysteine synthase

1

0

High-throughput

0.458

High

419807

SNF1
Carbon catabolite-derepressing protein kinase

1

0

High-throughput

0.458

High

485459

SSBP1
Single-stranded nucleic acid-binding protein

1

0

High-throughput

0.458

High

501190

MAK16
Protein MAK16

1

0

High-throughput

0.458

High

561215

APA1
Protein APA1 [Includes: Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 1

1

0

High-throughput

0.458

High

597206

PSA7
Probable proteasome subunit alpha type-7

1

0

High-throughput

0.458

High

597791

PWP1
Periodic tryptophan protein 1

1

0

High-throughput

0.458

High

612199

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.458

High

630161

RRP7
Ribosomal RNA-processing protein 7

1

0

High-throughput

0.458

High

630163

GBP2
Serine/arginine

1

0

High-throughput

0.458

High

630164

SRO9
RNA-binding protein SRO9

1

0

High-throughput

0.458

High

630167

GYS2
Glycogen [starch] synthase isoform 2

1

0

High-throughput

0.458

High

630168

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

0

High-throughput

0.458

High

630169

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

630174

DCA13
Protein SOF1

1

0

High-throughput

0.458

High

630176

URB1
Nucleolar pre-ribosomal-associated protein 1

1

0

High-throughput

0.458

High

630177

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.458

High

630178

UTP20
U3 small nucleolar RNA-associated protein 20

1

0

High-throughput

0.458

High

630180

DEF1
RNA polymerase II degradation factor 1

1

0

High-throughput

0.458

High

630182

EBP2
rRNA-processing protein EBP2

1

0

High-throughput

0.458

High

630183

YKH5
Uncharacterized protein YKL075C

1

0

High-throughput

0.458

High

630184

YKC3
Uncharacterized protein YKL023W

1

0

High-throughput

0.458

High

630185

RQT4
RQC trigger complex subunit RQT4

1

0

High-throughput

0.458

High

630186

YC16
UPF0743 protein YCR087C-A

1

0

High-throughput

0.458

High

630187

NOP4
Nucleolar protein 4

1

0

High-throughput

0.458

High

630192

SSF1
Ribosome biogenesis protein SSF1

1

0

High-throughput

0.458

High

630197

MET10
Sulfite reductase [NADPH] flavoprotein component

1

0

High-throughput

0.458

High

630198

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.458

High

630199

DLD3
D-2-hydroxyglutarate--pyruvate transhydrogenase DLD3

1

0

High-throughput

0.458

High

630200

DPO5
rDNA transcriptional regulator POL5

1

0

High-throughput

0.458

High

630201

NUG1
Nuclear GTP-binding protein NUG1

1

0

High-throughput

0.458

High

630202

UTP7
U3 small nucleolar RNA-associated protein 7

1

0

High-throughput

0.458

High

630203

IMB4
Importin subunit beta-4

1

0

High-throughput

0.458

High

630204

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

1

0

High-throughput

0.458

High

630206

RIO2
Serine/threonine-protein kinase RIO2

1

0

High-throughput

0.458

High

630207

UTP18
U3 small nucleolar RNA-associated protein 18

1

0

High-throughput

0.458

High

630208

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

630209

FAF1
Protein FAF1

1

0

High-throughput

0.458

High

630211

DIM1
Dimethyladenosine transferase

1

0

High-throughput

0.458

High

630212

KRI1
Protein KRI1

1

0

High-throughput

0.458

High

630214

LOC1
60S ribosomal subunit assembly/export protein LOC1

1

0

High-throughput

0.458

High

630215

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.458

High

630216

LSB3
LAS seventeen-binding protein 3

1

0

High-throughput

0.458

High

630221

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

0

High-throughput

0.458

High

630222

NOL10
Ribosome biogenesis protein ENP2

1

0

High-throughput

0.458

High

630224

UPF3
Nonsense-mediated mRNA decay protein 3

1

0

High-throughput

0.458

High

630230

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

High-throughput

0.458

High

630232

H1
Histone H1

1

0

High-throughput

0.458

High

630242

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

630243

UTP6
U3 small nucleolar RNA-associated protein 6

1

0

High-throughput

0.458

High

630246

NOG1
Nucleolar GTP-binding protein 1

1

0

High-throughput

0.458

High

630251

UTP15
U3 small nucleolar RNA-associated protein 15

1

0

High-throughput

0.458

High

630252

PUF6
Pumilio homology domain family member 6

1

0

High-throughput

0.458

High

630260

MRD1
Multiple RNA-binding domain-containing protein 1

1

0

High-throughput

0.458

High

630263

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.458

High

630264

ESF1
Pre-rRNA-processing protein ESF1

1

0

High-throughput

0.458

High

630265

MAG2
E3 ubiquitin-protein ligase MAG2

1

0

High-throughput

0.458

High

630266

RRP9
Ribosomal RNA-processing protein 9

1

0

High-throughput

0.458

High

630268

BFR2
Protein BFR2

1

0

High-throughput

0.458

High

630270

ELP1
Elongator complex protein 1

1

0

High-throughput

0.458

High

630271

HBT1
Protein HBT1

1

0

High-throughput

0.458

High

630273

RLP24
Ribosome biogenesis protein RLP24

1

0

High-throughput

0.458

High

630274

MTAP
S-methyl-5'-thioadenosine phosphorylase

1

0

High-throughput

0.458

High

630275

RCL1
RNA 3'-terminal phosphate cyclase-like protein

1

0

High-throughput

0.458

High

630280

NOP8
60S ribosome subunit biogenesis protein NOP8

1

0

High-throughput

0.458

High

630281

ETT1
Enhancer of translation termination 1

1

0

High-throughput

0.458

High

630283

UTP16
U3 small nucleolar RNA-associated protein 16

1

0

High-throughput

0.458

High

630286

FCF2
rRNA-processing protein FCF2

1

0

High-throughput

0.458

High

630290

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

630293

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

0

High-throughput

0.458

High

630299

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.458

High

490442

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

493288

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

510377

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

630171

HSP79
Heat shock protein homolog SSE2

1

2

High-throughput

0.445

High

630205

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

365852

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.426

High

520580

YPK1
Serine/threonine-protein kinase YPK1

1

0

High-throughput

0.426

High

630162

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

630173

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.426

High

630220

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.426

High

393525

PMA1
Plasma membrane ATPase 1

1

0

High-throughput

0.249

Low

630172

MG101
Mitochondrial genome maintenance protein MGM101

1

0

High-throughput

0.249

Low

630210

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.249

Low

630226

SEH1
Nucleoporin SEH1

1

0

High-throughput

0.249

Low

630254

RTN1
Reticulon-like protein 1

1

0

High-throughput

0.249

Low

630278

ZEO1
Protein ZEO1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024