HitPredict

Interactor 1: KIF5A (Q6QLM7)
Kinesin heavy chain isoform 5A (EC 5.6.1.3) (Kinesin heavy chain neuron-specific 1) (Neuronal kinesin heavy chain) (NKHC)
Gene: KIF5A

Interactor 2: TRAK2 (Q8R2H7)
Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein homolog) (GABA-A receptor-interacting factor 1) (GRIF-1) (O-GlcNAc transferase-interacting protein of 98 kDa)
Gene: TRAK2

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15644324
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0019894 - kinesin binding GO:0030425 - dendrite GO:0032839 - dendrite cytoplasm GO:0043025 - neuronal cell body
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1027 Rn			1 913
+	Hs
		244846 KIF5A_HUMAN (1-1027): 6.7e-148: 469: 96.51		TRAK2_HUMAN (1-913): 5.54e-139: 438: 86.45
+	Hs
		244827 KIF1B_HUMAN (6-736): 6.02e-101: 351: 23.52		TRAK2_HUMAN (1-913): 5.54e-139: 438: 86.45
+	Mm
		205353 KIF5A_MOUSE (1-1027): 5.43e-150: 474: 98.44		HAP1_MOUSE (93-410): 3.31e-30: 129: 23.91
+	Rn
		1179645 KINH_RAT (595-1024): 1.71e-16: 86.8: 10.53		TRAK2_RAT (1-913): 1.06e-142: 448: 100.00
+	Hs
		1087040 KIF5A_HUMAN (1-1027): 6.7e-148: 469: 96.51		TRAK1_HUMAN (16-258): 9.87e-10: 64.5: 9.84
+	Hs
		244833 KINH_HUMAN (595-1024): 2.46e-16: 86.5: 10.53		TRAK2_HUMAN (1-913): 5.54e-139: 438: 86.45
+	Hs
		244116 KIF5C_HUMAN (538-997): 5.49e-13: 75.3: 10.02		TRAK2_HUMAN (1-913): 5.54e-139: 438: 86.45
+	Hs
		773038 KI13B_HUMAN (7-730): 1.03e-109: 377: 23.04		MYH9_HUMAN (10-650): 1.24e-23: 110: 9.61
+	Hs
		331576 KIF4B_HUMAN (333-774): 1.81e-10: 67.5: 16.23		KIF4A_HUMAN (134-524): 2.12e-50: 195: 18.47
+	Rn
		928159 KINH_RAT (595-1024): 1.71e-16: 86.8: 10.53		HAP1_RAT (93-408): 4.02e-30: 129: 24.93
+	Rn
		928148 KIF5C_RAT (541-997): 7.22e-14: 78.4: 9.45		HAP1_RAT (93-408): 4.02e-30: 129: 24.93
+	Dm
		120099 KINH_DROME (429-1010): 1.2e-12: 74.5: 10.58		M9PCD4_DROME (1-574): 1.53e-29: 128: 11.51
+	Dm
		602976 KINH_DROME (429-1010): 1.2e-12: 74.5: 10.58		MILT_DROME (86-360): 1.35e-28: 125: 29.09
+	Hs
		535925 KINH_HUMAN (595-1024): 2.46e-16: 86.5: 10.53		MYH3_HUMAN (6-559): 2.05e-20: 99: 11.99
+	Hs
		750024 KINH_HUMAN (595-1024): 2.46e-16: 86.5: 10.53		TRAK1_HUMAN (16-258): 9.87e-10: 64.5: 9.84
+	Hs
		91641 KINH_HUMAN (595-1024): 2.46e-16: 86.5: 10.53		C9JC32_HUMAN (1-230): 4.32e-09: 62.6: 11.49
+	Hs
		244195 KIF5C_HUMAN (538-997): 5.49e-13: 75.3: 10.02		TRAK1_HUMAN (16-258): 9.87e-10: 64.5: 9.84