HitPredict

Interactor 1: CRTC1 (Q6UUV9)
CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1) (Transducer of regulated cAMP response element-binding protein 1) (TORC-1) (Transducer of CREB protein 1)
Gene: CRTC1

Interactor 2: CR3L2 (Q70SY1)
Cyclic AMP-responsive element-binding protein 3-like protein 2 (cAMP-responsive element-binding protein 3-like protein 2) (BBF2 human homolog on chromosome 7) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 2]
Gene: CREB3L2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	TORC_N~bZIP_1
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 634 Hs			1 520
+	Hs
		1198333 CRTC2_HUMAN (2-634): 3.19e-31: 131: 33.00		CR3L2_HUMAN (1-520): 1.06e-121: 368: 100.00
+	Hs
		1224835 TENS2_HUMAN (213-596): 1.04e-26: 118: 16.83		CR3L2_HUMAN (1-520): 1.06e-121: 368: 100.00
+	Hs
		1248103 CRTC3_HUMAN (2-634): 6.47e-22: 102: 26.94		CR3L2_HUMAN (1-520): 1.06e-121: 368: 100.00
+	Hs
		1258553 CIC_HUMAN (31-553): 4.08e-12: 71.8: 11.41		CR3L2_HUMAN (1-520): 1.06e-121: 368: 100.00
+	Hs
		617307 CRTC2_HUMAN (2-634): 3.19e-31: 131: 33.00		ATF6A_HUMAN (75-482): 2.75e-37: 148: 13.87
+	Mm
		104685 CRTC2_MOUSE (2-634): 6.47e-29: 124: 33.62		ATF6A_MOUSE (98-482): 4.49e-34: 138: 13.51
+	Hs
		605271 CIC_HUMAN (31-553): 4.08e-12: 71.8: 11.41		ATF7_HUMAN (34-367): 4.65e-32: 130: 15.58
+	Hs
		617114 CIC_HUMAN (31-553): 4.08e-12: 71.8: 11.41		ATF1_HUMAN (163-345): 2.76e-11: 66.2: 17.94