Protein: CRTC3
CREB-regulated transcription coactivator 3 (Transducer of regulated cAMP response element-binding protein 3) (TORC-3) (Transducer of CREB protein 3)

Gene: CRTC3
Organism: Homo sapiens
Interactions: 59
UniProt ID: Q6UUV7

Gene Ontology (top 5):
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

729967

1433B
14-3-3 protein beta/alpha

6

20

High-throughput

0.730

High

966491

1433G
14-3-3 protein gamma

5

20

High-throughput

0.718

High

848788

MAGAA
Melanoma-associated antigen 10

4

1

High-throughput

0.691

High

1049444

1433F
14-3-3 protein eta

4

20

High-throughput

0.691

High

691145

1433T
14-3-3 protein theta

3

20

High-throughput

0.650

High

593136

CREB1
Cyclic AMP-responsive element-binding protein 1

1

2

High-throughput

0.618

High

971665

1433E
14-3-3 protein epsilon

2

6

High-throughput

0.611

High

990372

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.611

High

1248115

CPAP
Centrosomal P4.1-associated protein

2

4

High-throughput

0.611

High

1248106

CAH13
Carbonic anhydrase 13

2

0

High-throughput

0.580

High

1248103

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

4

High-throughput

0.575

High

1248112

SIK2
Serine/threonine-protein kinase SIK2

1

5

Small-scale

0.561

High

1198985

KLH12
Kelch-like protein 12

1

1

High-throughput

0.560

High

535203

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.536

High

682525

S100P
Protein S100-P

1

2

High-throughput

0.536

High

853703

MK08
Mitogen-activated protein kinase 8

1

3

High-throughput

0.536

High

964647

DCAF7
DDB1- and CUL4-associated factor 7

1

9

High-throughput

0.536

High

1026092

CLH1
Clathrin heavy chain 1

1

6

High-throughput

0.536

High

1154654

VAMP3
Vesicle-associated membrane protein 3

1

2

High-throughput

0.536

High

1248114

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.536

High

1248118

GTSE1
G2 and S phase-expressed protein 1

1

6

High-throughput

0.536

High

702984

DPOD1
DNA polymerase delta catalytic subunit

1

0

High-throughput

0.513

High

922736

CCHL
Holocytochrome c-type synthase

1

0

High-throughput

0.513

High

862237

YAP1
Transcriptional coactivator YAP1

1

20

High-throughput

0.501

High

706178

S10A2
Protein S100-A2

1

2

High-throughput

0.489

High

1120568

LRP8
Low-density lipoprotein receptor-related protein 8

1

1

High-throughput

0.489

High

1248116

K1549
UPF0606 protein KIAA1549

1

11

High-throughput

0.489

High

143063

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

172972

XPO1
Exportin-1

1

9

High-throughput

0.479

High

377616

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

1

High-throughput

0.479

High

474074

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

730693

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

888136

MCM2
DNA replication licensing factor MCM2

1

2

High-throughput

0.479

High

1028247

MDM2
E3 ubiquitin-protein ligase Mdm2

1

1

Small-scale

0.479

High

1033032

EWS
RNA-binding protein EWS

1

7

High-throughput

0.479

High

1048010

TLE3
Transducin-like enhancer protein 3

1

14

High-throughput

0.479

High

1087815

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

1133480

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

1140448

KIF14
Kinesin-like protein KIF14

1

7

High-throughput

0.479

High

1248104

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

7

High-throughput

0.479

High

1248105

KSR1
Kinase suppressor of Ras 1

1

10

High-throughput

0.479

High

1248107

NUP35
Nucleoporin NUP35

1

4

High-throughput

0.479

High

1248108

NEDD1
Protein NEDD1

1

8

High-throughput

0.479

High

1248109

HDAC2
Histone deacetylase 2

1

8

High-throughput

0.479

High

1248110

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

15

Small-scale

0.479

High

1248113

PKHA4
Pleckstrin homology domain-containing family A member 4

1

9

High-throughput

0.479

High

1248117

KI13B
Kinesin-like protein KIF13B

1

7

High-throughput

0.479

High

1248121

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1248122

XPO7
Exportin-7

1

9

High-throughput

0.479

High

1248123

ZBT21
Zinc finger and BTB domain-containing protein 21

1

1

High-throughput

0.479

High

1248124

CBY1
Protein chibby homolog 1

1

2

High-throughput

0.479

High

551112

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.458

High

1248120

CING
Cingulin

1

1

High-throughput

0.437

High

1248125

KCTD3
BTB/POZ domain-containing protein KCTD3

1

6

High-throughput

0.437

High

717867

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

0

High-throughput

0.426

High

1206663

LRC73
Leucine-rich repeat-containing protein 73

1

0

High-throughput

0.279

Low

1248119

CFA97
Cilia- and flagella-associated protein 97

1

0

High-throughput

0.279

Low

1248126

PCDBF
Protocadherin beta-15

1

0

High-throughput

0.279

Low

1248111

ACE2
Angiotensin-converting enzyme 2

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025