HitPredict

Interactor 1: PUM2 (Q8TB72)
Pumilio homolog 2 (Pumilio-2)
Gene: PUM2

Interactor 2: DAZL (Q92904)
Deleted in azoospermia-like (DAZ homolog) (DAZ-like autosomal) (Deleted in azoospermia-like 1) (SPGY-like-autosomal)
Gene: DAZL

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.637

Property	Details
Experiments	29395067, 12511597, 15806553
Identification Methods	proximity labelling technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003730 - mRNA 3'-UTR binding GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1066 Hs			1 295
+	Hs
		1238763 PUM2_HUMAN (1-1066): 0: 992: 100.00		BOLL_HUMAN (30-267): 8.63e-40: 142: 29.20
+	Hs
		1024853 PUM2_HUMAN (1-1066): 0: 992: 100.00		DAZ2_HUMAN (1-247): 1.23e-34: 133: 66.53
+	Hs
		1056714 PUM1_HUMAN (1-1066): 0: 885: 76.67		DAZL_HUMAN (1-295): 1.71e-75: 234: 100.00
+	Hs
		1252129 PUM2_HUMAN (1-1066): 0: 992: 100.00		DAZ1_HUMAN (2-171): 1.6e-25: 107: 82.94
+	Hs
		516599 PUM2_HUMAN (1-1066): 0: 992: 100.00		PABP1_HUMAN (32-126): 2.67e-16: 81: 18.37
+	Hs
		668394 PUM2_HUMAN (1-1066): 0: 992: 100.00		RBMS1_HUMAN (36-125): 1.7e-09: 59.9: 21.98
+	Hs
		1031329 PUM1_HUMAN (1-1066): 0: 885: 76.67		PABP4_HUMAN (34-126): 1.28e-17: 84.8: 19.79
+	Hs
		516519 PUM1_HUMAN (1-1066): 0: 885: 76.67		PABP1_HUMAN (32-126): 2.67e-16: 81: 18.37
+	Hs
		668357 PUM1_HUMAN (1-1066): 0: 885: 76.67		RBMS1_HUMAN (36-125): 1.7e-09: 59.9: 21.98
+	Sc
		376947 PUF3_YEAST (870-1061): 2.57e-27: 121: 24.48		PABP_YEAST (18-126): 6.81e-17: 82.5: 18.75
+	Dm
		597047 PUM_DROME (826-1060): 1.16e-22: 107: 22.55		PABP_DROME (41-126): 5.98e-16: 79.8: 20.23