Protein: ASPP1
Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B)

Gene: ASPP1, PPP1R13B
Organism: Homo sapiens
Interactions: 168
UniProt ID: Q96KQ4

Gene Ontology (top 5):
GO:0002039 - p53 binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

212780

SRGP3
SLIT-ROBO Rho GTPase-activating protein 3

3

8

High-throughput

0.861

High

1396266

LATS2
Serine/threonine-protein kinase LATS2

3

13

Small-scale

0.827

High

414419

P53
Cellular tumor antigen p53

2

16

Small-scale

0.789

High

271634

LIPA3
Liprin-alpha-3

2

5

High-throughput

0.783

High

325403

DIRA1
GTP-binding protein Di-Ras1

2

7

High-throughput

0.783

High

682088

RBTN1
Rhombotin-1

2

14

High-throughput

0.783

High

1145912

RBP1
RalA-binding protein 1

2

13

High-throughput

0.783

High

1347355

LMO3
LIM domain only protein 3

2

14

High-throughput

0.783

High

1365830

HMHA1
Rho GTPase-activating protein 45 [Cleaved into: Minor histocompatibility antigen HA-1

2

11

High-throughput

0.783

High

1396263

KIF9
Kinesin-like protein KIF9

2

7

High-throughput

0.783

High

967916

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

12

20

Small-scale

0.762

High

1396274

TNIK
TRAF2 and NCK-interacting protein kinase

2

20

High-throughput

0.762

High

786785

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

10

20

Small-scale

0.758

High

349207

LATS1
Serine/threonine-protein kinase LATS1

2

15

Small-scale

0.754

High

1396278

NINL
Ninein-like protein

2

16

High-throughput

0.754

High

968409

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

4

20

High-throughput

0.706

High

1396253

KIFC3
Kinesin-like protein KIFC3

2

1

High-throughput

0.700

High

1039113

RASF7
Ras association domain-containing protein 7

4

12

High-throughput

0.699

High

668693

APC
Adenomatous polyposis coli protein

1

20

High-throughput

0.698

High

1396264

PKHA5
Pleckstrin homology domain-containing family A member 5

1

20

High-throughput

0.698

High

132239

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

11

High-throughput

0.691

High

987450

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

1

High-throughput

0.691

High

1382368

SPSB4
SPRY domain-containing SOCS box protein 4

1

16

High-throughput

0.691

High

1396247

CDC5L
Cell division cycle 5-like protein

4

6

High-throughput

0.688

High

1340405

RASF8
Ras association domain-containing protein 8

7

11

High-throughput

0.682

High

186790

P73
Tumor protein p73

1

16

Small-scale

0.681

High

1396261

P63
Tumor protein 63

1

16

Small-scale

0.681

High

636882

GSTM3
Glutathione S-transferase Mu 3

3

2

High-throughput

0.667

High

239174

ZNRD2
Protein ZNRD2

3

2

High-throughput

0.662

High

833341

PERI
Peripherin

3

14

High-throughput

0.653

High

1227268

A16L1
Autophagy-related protein 16-1

3

20

Small-scale

0.633

High

1154565

CC85B
Coiled-coil domain-containing protein 85B

2

8

High-throughput

0.628

High

799398

BRCA1
Breast cancer type 1 susceptibility protein

1

6

High-throughput

0.621

High

363723

EGFR
Epidermal growth factor receptor

1

14

High-throughput

0.618

High

374856

RASH
GTPase HRas

1

8

Small-scale

0.618

High

411005

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

11

Small-scale

0.618

High

440177

LCK
Tyrosine-protein kinase Lck

1

15

High-throughput

0.618

High

463708

LYN
Tyrosine-protein kinase Lyn

1

15

High-throughput

0.618

High

541641

FGFR1
Fibroblast growth factor receptor 1

1

17

High-throughput

0.618

High

710431

EPHA2
Ephrin type-A receptor 2

1

18

High-throughput

0.618

High

710880

EPHB2
Ephrin type-B receptor 2

1

12

High-throughput

0.618

High

764968

CTNB1
Catenin beta-1

1

13

High-throughput

0.618

High

955480

CDC42
Cell division control protein 42 homolog

1

15

High-throughput

0.618

High

981639

RAN
GTP-binding nuclear protein Ran

1

9

Small-scale

0.618

High

1004164

CXAR
Coxsackievirus and adenovirus receptor

1

5

High-throughput

0.618

High

1058916

ZO1
Tight junction protein 1

1

15

High-throughput

0.618

High

1108046

SQSTM
Sequestosome-1

1

13

High-throughput

0.618

High

1396273

ZO2
Tight junction protein 2

1

9

High-throughput

0.618

High

1326308

NIN
Ninein

2

20

High-throughput

0.611

High

164053

NDC80
Kinetochore protein NDC80 homolog

2

19

High-throughput

0.606

High

225665

AAKB2
5'-AMP-activated protein kinase subunit beta-2

2

3

High-throughput

0.606

High

262422

DTNB
Dystrobrevin beta

2

7

High-throughput

0.606

High

634583

LMNB1
Lamin-B1

2

12

High-throughput

0.606

High

777408

K1C20
Keratin, type I cytoskeletal 20

2

8

High-throughput

0.606

High

821182

TXLNA
Alpha-taxilin

2

8

High-throughput

0.606

High

940461

TCL1A
T-cell leukemia/lymphoma protein 1A

2

1

High-throughput

0.606

High

956682

CKS1
Cyclin-dependent kinases regulatory subunit 1

2

1

High-throughput

0.606

High

1053426

DEUP1
Deuterosome assembly protein 1

2

11

High-throughput

0.606

High

1108851

BFSP2
Phakinin

2

8

High-throughput

0.606

High

1228702

C102B
Coiled-coil domain-containing protein 102B

2

12

High-throughput

0.606

High

1239730

PPR18
Phostensin

2

10

High-throughput

0.606

High

1294168

CEP57
Centrosomal protein of 57 kDa

2

1

High-throughput

0.606

High

1295613

RASL3
RAS protein activator like-3

2

7

High-throughput

0.606

High

1327441

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

2

7

High-throughput

0.606

High

1333009

F184A
Protein FAM184A

2

7

High-throughput

0.606

High

1340859

GA2L2
GAS2-like protein 2

2

5

High-throughput

0.606

High

1348430

LNX1
E3 ubiquitin-protein ligase LNX

2

15

High-throughput

0.606

High

1350698

CCHCR
Coiled-coil alpha-helical rod protein 1

2

9

High-throughput

0.606

High

1358982

TEKT4
Tektin-4

2

2

High-throughput

0.606

High

1368933

GOGA1
Golgin subfamily A member 1

2

12

High-throughput

0.606

High

1396251

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

2

11

High-throughput

0.606

High

1396257

TSG10
Testis-specific gene 10 protein

2

16

High-throughput

0.606

High

1396267

SALL1
Sal-like protein 1

2

6

High-throughput

0.606

High

1396271

HM20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

2

14

High-throughput

0.606

High

1396276

NP1L2
Nucleosome assembly protein 1-like 2

2

5

High-throughput

0.606

High

1059926

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

2

5

Small-scale

0.594

High

827464

MLH1
DNA mismatch repair protein Mlh1

2

0

High-throughput

0.580

High

1315041

ZZZ3
ZZ-type zinc finger-containing protein 3

2

0

High-throughput

0.580

High

1329992

TEX9
Testis-expressed protein 9

2

0

High-throughput

0.580

High

1390145

MCRS1
Microspherule protein 1

2

0

High-throughput

0.580

High

1396248

TS101
Tumor susceptibility gene 101 protein

2

0

High-throughput

0.580

High

1396250

SLD5
DNA replication complex GINS protein SLD5

2

0

High-throughput

0.580

High

1396255

DGC6L
Protein DGCR6L

2

0

High-throughput

0.580

High

1396268

CB042
Uncharacterized protein C2orf42

2

0

High-throughput

0.580

High

1396270

MS18A
Protein Mis18-alpha

2

0

High-throughput

0.580

High

1396281

CAN7
Calpain-7

2

0

High-throughput

0.580

High

1396244

CEP63
Centrosomal protein of 63 kDa

2

12

High-throughput

0.576

High

66651

CC85C
Coiled-coil domain-containing protein 85C

2

8

High-throughput

0.574

High

1093924

TRAF1
TNF receptor-associated factor 1

1

8

High-throughput

0.573

High

1351575

MIPT3
TRAF3-interacting protein 1

2

5

High-throughput

0.565

High

211588

SIAH2
E3 ubiquitin-protein ligase SIAH2

1

12

Small-scale

0.561

High

322857

MTCL2
Microtubule cross-linking factor 2

2

10

High-throughput

0.553

High

337511

MATN4
Matrilin-4

2

2

High-throughput

0.553

High

1042053

LMNB2
Lamin-B2

2

9

High-throughput

0.553

High

1194756

ACSF3
Malonate--CoA ligase ACSF3, mitochondrial

2

1

High-throughput

0.553

High

1295086

F90A1
Protein FAM90A1

2

1

High-throughput

0.553

High

1198158

CC184
Coiled-coil domain-containing protein 184

1

0

High-throughput

0.549

High

1350346

MIPO1
Mirror-image polydactyly gene 1 protein

1

0

High-throughput

0.549

High

66514

RASFA
Ras association domain-containing protein 10

1

4

High-throughput

0.536

High

296894

RASF9
Ras association domain-containing protein 9

1

11

High-throughput

0.536

High

347254

BAG2
BAG family molecular chaperone regulator 2

1

8

High-throughput

0.536

High

549662

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

2

High-throughput

0.536

High

593866

PP2BB
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

1

20

High-throughput

0.536

High

789199

NUP62
Nuclear pore glycoprotein p62

1

11

High-throughput

0.536

High

883935

CENPF
Centromere protein F

1

20

High-throughput

0.536

High

979143

RS6
Small ribosomal subunit protein eS6

1

3

High-throughput

0.536

High

1067608

EP300
Histone acetyltransferase p300

1

20

Small-scale

0.536

High

1068853

IFFO1
Non-homologous end joining factor IFFO1

1

7

High-throughput

0.536

High

1148869

PP1R7
Protein phosphatase 1 regulatory subunit 7

1

9

High-throughput

0.536

High

1251507

CD109
CD109 antigen

1

2

High-throughput

0.536

High

1334515

RN149
E3 ubiquitin-protein ligase RNF149

1

6

High-throughput

0.536

High

1340643

NEDD1
Protein NEDD1

1

11

High-throughput

0.536

High

1396246

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

1

6

High-throughput

0.536

High

1396252

CP250
Centrosome-associated protein CEP250

1

11

High-throughput

0.536

High

1396275

ODF2L
Protein BCAP

1

16

High-throughput

0.536

High

1396280

RBGP1
Rab GTPase-activating protein 1

1

1

High-throughput

0.536

High

245353

CE104
Centrosomal protein of 104 kDa

1

1

High-throughput

0.515

High

283132

PSIP1
PC4 and SFRS1-interacting protein

1

6

High-throughput

0.515

High

618158

K2C4
Keratin, type II cytoskeletal 4

1

5

High-throughput

0.515

High

284709

KHDR3
KH domain-containing, RNA-binding, signal transduction-associated protein 3

1

5

Small-scale

0.501

High

1216331

IFFO2
Intermediate filament family orphan 2

1

7

High-throughput

0.489

High

1396245

CC85A
Coiled-coil domain-containing protein 85A

1

8

High-throughput

0.489

High

1396262

CPVL
Probable serine carboxypeptidase CPVL

1

1

High-throughput

0.489

High

1396272

CING
Cingulin

1

9

High-throughput

0.481

High

159805

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

15

High-throughput

0.479

High

299333

FLOT1
Flotillin-1

1

3

High-throughput

0.479

High

436970

K1C18
Keratin, type I cytoskeletal 18

1

7

High-throughput

0.479

High

437302

K2C8
Keratin, type II cytoskeletal 8

1

5

High-throughput

0.479

High

475662

K1C19
Keratin, type I cytoskeletal 19

1

4

High-throughput

0.479

High

556288

CADH1
Cadherin-1

1

3

High-throughput

0.479

High

688298

TTP
mRNA decay activator protein ZFP36

1

2

High-throughput

0.479

High

764410

CTNA1
Catenin alpha-1

1

5

High-throughput

0.479

High

896611

VASP
Vasodilator-stimulated phosphoprotein

1

7

High-throughput

0.479

High

936412

AFAD
Afadin

1

20

High-throughput

0.479

High

1087247

STX4
Syntaxin-4

1

5

High-throughput

0.479

High

1141866

EEA1
Early endosome antigen 1

1

8

High-throughput

0.479

High

1143475

PCM1
Pericentriolar material 1 protein

1

1

High-throughput

0.479

High

1152204

MARE1
Microtubule-associated protein RP/EB family member 1

1

5

High-throughput

0.479

High

1156577

CCDC6
Coiled-coil domain-containing protein 6

1

19

High-throughput

0.479

High

1159803

OCLN
Occludin

1

4

High-throughput

0.479

High

1197057

AMOT
Angiomotin

1

20

High-throughput

0.479

High

1226223

CP135
Centrosomal protein of 135 kDa

1

11

High-throughput

0.479

High

1229039

RNF43
E3 ubiquitin-protein ligase RNF43

1

5

High-throughput

0.479

High

1252182

SYNE3
Nesprin-3

1

18

High-throughput

0.479

High

1252365

MEX3B
RNA-binding protein MEX3B

1

1

High-throughput

0.479

High

1287117

PATL1
Protein PAT1 homolog 1

1

9

High-throughput

0.479

High

1288969

EST1A
Telomerase-binding protein EST1A

1

5

High-throughput

0.479

High

1353244

PARD3
Partitioning defective 3 homolog

1

17

High-throughput

0.479

High

1372269

H2B1H
Histone H2B type 1-H

1

20

High-throughput

0.479

High

1396249

LZTS2
Leucine zipper putative tumor suppressor 2

1

20

High-throughput

0.479

High

1396256

CPEB1
Cytoplasmic polyadenylation element-binding protein 1

1

5

High-throughput

0.479

High

1396258

UNK
RING finger protein unkempt homolog

1

5

High-throughput

0.479

High

1396259

WWTR1
WW domain-containing transcription regulator protein 1

1

19

High-throughput

0.479

High

1396260

VP33B
Vacuolar protein sorting-associated protein 33B

1

5

High-throughput

0.479

High

1396265

E41LA
Band 4.1-like protein 4A

1

16

High-throughput

0.479

High

1396269

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

3

High-throughput

0.479

High

1396277

ADIP
Afadin- and alpha-actinin-binding protein

1

1

High-throughput

0.479

High

86314

B9EK46
Cingulin

1

9

High-throughput

0.470

High

1205206

NHSL2
NHS-like protein 2

1

7

High-throughput

0.470

High

327413

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.458

High

1163660

PPR3A
Protein phosphatase 1 regulatory subunit 3A

1

2

High-throughput

0.437

High

1256560

CE128
Centrosomal protein of 128 kDa

1

15

High-throughput

0.437

High

1385679

ENTR1
Endosome-associated-trafficking regulator 1

1

3

High-throughput

0.437

High

1395376

NEUL4
Neuralized-like protein 4

1

1

High-throughput

0.407

High

506762

PRR35
Proline-rich protein 35

2

0

High-throughput

0.316

High

1332422

CBY2
Protein chibby homolog 2

2

0

High-throughput

0.316

High

1396254

TEX12
Testis-expressed protein 12

2

0

High-throughput

0.316

High

1396279

TMED5
Transmembrane emp24 domain-containing protein 5

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025