Interactor 1: ZN675 (Q8TD23)
Zinc finger protein 675 (TRAF6-binding zinc finger protein) (TRAF6-inhibitory zinc finger protein)
Gene: ZNF675

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 0.60 0.573

The method score is based on:

Property Details
Experiments 11751921
Identification Methods affinity chromatography technology, two hybrid, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0007249 - canonical NF-kappaB signal transduction
GO:0008270 - zinc ion binding
GO:0045453 - bone resorption
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 568
Hs

1 522
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024